PhD Position (f/m/x) - Personalized Risk Prediction Using Genomic Data

at  Helmholtz Zentrum Mnchen

102543
Full time
39 hrs/week
Neuherberg near Munich
Home Office Options
We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.
Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.
Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.
This is what drives us. Why not join us and make a difference?
The Institute of Epidemiology invites applications for a PhD position (f/m/x) in Genomic Data Science as part of the . Funded by the European Union’s Horizon Europe Research and Innovation Program, this project focuses on Personalized Risk Prevention in Digital Health, with a particular emphasis on healthy ageing.
We are looking for a highly motivated individual to contribute to improving personalized risk prediction for cardiovascular disease using polygenic risk scores (PRS).

“This research will empower individuals by providing them with actionable genetic insights to enhance their health decisions.”
Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich: “We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.
Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization.”
Your tasks

Year 1

• Implement and improve a genotyping pipeline for calculating PRS specific to cardiovascular disease.
• Coordinate genotype measurements and manage data imputation on an established server.
• Harmonize genomic datasets and ensure data consistency.
• Calculate PRS and validate methods according to established standards.
• Prepare outputs for medical application.

Please refer the Job description for details