Post-doctoral position in Cancer Metabolism Research

at  Luxembourg Institute of Health

BACKGROUND

Chronic Lymphocytic Leukemia (CLL) represents the most frequent leukemia in adults. Despite recent advances in treatments, CLL remains a deadly uncurable disease. This cancer is caracterized by an accumulation of abnormal, apoptosis resistant, B lymphocytes in the blood and lymphoid organs of the patients. CLL progression is highly dependent on complex interactions between tumor cells and their microenvironment. We demonstrated that dysregulated One carbon metabolism is an important feature of CLL, that can be efficiently targeted by new first-in-class MTHFD1 inhibitor.

KEY SKILLS, EXPERIENCE AND QUALIFICATIONS

• PhD in Biochemistry, Biomedical Sciences or Immunology. Prior experience in cancer research or cancer metabolism would be an advantage.
• Experience in cell culture, biochemistry, molecular biology, imaging, flow-cytometry required.
• Excellent time management, rigor, perseverance, scientific creativity and originality, writing skills, sense of priority and ability to work with others.
• Fluency in English is mandatory.

Please refer the Job description for details