Postdoc in Metabolomics, Microbiome, and Cardiometabolic health

at  Kbenhavns Universitet

Are you interested in pursuing a career within metabolomics, microbiome and cardiometabolic health? Are you good at working independently, but also enjoy being part of an ambitious and collaborating team? Then you might be our new postdoc! The position is to be filled by 1 April 2025 or as soon as possible thereafter.
The position is affiliated to Microbiome Health Initiative (MHI) funded by the Novo Nordisk Foundation. The objectives of MHI are to determine the causal role(s) of the gut microbiome for cardiometabolic diseases (CMDs) and to utilize this knowledge to investigate strategies for developing microbiome-based interventions to prevent and/or treat CMDs in humans. The ambitious MHI virtual centre involves top research environments in Denmark and throughout Europe with complementary competencies.
The postdoc will apply state-of-the-art metabolomics on samples from pre-clinical studies and already conducted human studies to identify microbial metabolites that are intrinsically associated with CMD processes and that could be regulated through foods to produce a desired therapeutic effect. The postdoc will seek to understand how these microbial metabolites are regulated and associated with gut microbiome composition, gut environment, diet, and markers of cardiometabolic health.

We are looking for a motivated postdoctoral researcher interested in studying the role of gut microbial metabolites in cardiometabolic health by performing metabolomics analyses and integrating omics-data from human studies. Additionally, the candidate will be involved in the supervision of the group’s Ph.D., Master and Bachelor students. The work will involve:

• Sample preparation and analysis of human samples with targeted and untargeted liquid chromatography mass spectrometry (LC-MS) - based metabolomics
• LC-MS data extraction and preprocessing using R
• Integration of diet, microbiome and metabolomics data with statistical analyses using R
• Collaboration with other researchers, technicians and students affiliated to the project
• Dissemination of results in the form conference contributions and scientific publications
• Teaching on nutrition, microbiome and metabolomics courses depending on interests/expertise

The candidate we seek

• Has a PhD degree in metabolomics, chemometrics, bioinformatics or other related areas
• Has demonstrated expertise in mass-spectrometric data analyses (e.g. metabolomics)
• Has demonstrated expertise in omics data integration and flair for R programming
• Has an excellent publication track record (or equivalent experience) and strong scientific drive
• Is motivated by both personal and team accomplishments
• Thrives on multidisciplinary collaboration and is curious and open-minded
• Has experience and a proven track record of successful collaboration in diverse research environments

As a formal requirement, you must hold a PhD degree (or equivalent). Experience with human nutritional/microbiome intervention/cohort studies is favorable, but not a requirement.