Postdoc in retinal pathophysiology

at  Aarhus Universitet

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of vision science/retinal biology and retinal pathophysiology as per 1 April 2025 or as soon as possible thereafter. The position is a fixed-term full-time position for 2 years.
The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department’s modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research.

ABOUT THE RESEARCH PROJECT

We are seeking a highly motivated postdoctoral researcher to explore the role of sortilin in the development of pathological blood vessel growth related to wet age-related macular degeneration (AMD). This project aims to uncover how the receptor might influence both the immune and angiogenic pathways in the retina, ultimately helping to identify new therapeutic targets beyond current treatments. The successful candidate will use molecular, cellular, and in vivo approaches in a dynamic, multidisciplinary environment at the forefront of vision research in Denmark. The position is in biomedical research at the intersection of vision science, immunology, and vascular biology, with a focus on understanding and treating pathological processes in the retina.

TERMS OF EMPLOYMENT

• Appointment as a postdoc requires academic qualifications at PhD level.
• Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
• The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
• Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
• The yearly base salary for a fulltime postdoc is between DKK 484.214,84 and DKK 538.720,20 depending on the years of working experience after achieved MSc degree. The base salary includes a position related supplement and pension (17.1 %). Additional supplement(s) for special qualifications can be negotiated. Authorisation supplemement(s) will be granted, if relevant for the position. Your local eligible trade union representative at Aarhus University negotiates your salary on your behalf.
• Researchers recruited from abroad are offered a special researcher tax scheme with a lower tax rate.
• Further information on qualification requirements and job description can be found in the Ministerial Order on Job Structure for Academic Staff

Your position is primarily research-based but will also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

Your main tasks will consist of:

• Independent research of high international quality
• Immunofluorescence and flow cytometry to examine immune cell recruitment in the retina of normal vs knockout mice
• Single-cell RNA-seq and protein analyses to examine changes in the transcriptome and secretome of immune and RPE cells in normal vs knockout mice
• Phenotypic and functional characterization of receptor-knockout cells in vitro and in vivo.
• Analysis, interpretation, and presentation of research data including publication in peer-reviewed journals
• Participation and presentation at national and international conferences.
• (Co-)supervision of master and PhD students
• Work as part of a multidisciplinary team

You will report to the Professor Thomas Corydon.