Postdoctoral Associate - Amyloid Strain Differences in Alzheimer's Disease

at  Baylor College of Medicine

SUMMARY

Are you passionate about deciphering the complexities of Alzheimer’s disease? We’re seeking a smart and dedicated scientist to help us probe the hidden heterogeneity of Alzheimer’s pathology. The Jankowsky lab is on a mission to understand how individual differences in Alzheimer’s onset and symptoms stem from structural variations of protein aggregation within the brain. Our focus revolves around the pivotal role of amyloid plaques in Alzheimer’s pathology, recognizing that these aggregates can manifest in diverse forms. Some may drive disease progression, while others could hold protective qualities

MINIMUM QUALIFICATIONS

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

PREFERRED QUALIFICATIONS

• Strong background in molecular biology - Western blotting, ELISA, immunofluorescence, etc. These techniques are fundamental to our experimental work.
• Experience with amyloid or tau biology - these proteins are key determinants of disease.
• Experience with mouse models for Alzheimer’s disease or other neurodegenerative diseases. These models form the basis of our studies.
• Beyond the bench, our ideal candidate is also highly self-motivated, detail-oriented and able to think independently, but also work well in a team.

• Designs and conducts smart, impactful experiments to identify the cost-benefit balance between route of delivery and therapeutic efficacy.
• Discovers, discusses, and deploys new research ideas towards the goal of making gene therapy a reality for neurological disease.
• Carefully collects and exhaustively analyzes experimental results to conclusively test each hypothesis.
• Plunders the literature for new ideas, methods, and resources.
• Scrutinizes results, interpret outcomes, identify next steps from each experiment.
• Communicates the rationale, design, data, and impact of our work to others in the field in clear prose and visually effective figures.