Postdoctoral Fellow - In situ structural biology of SARM1

at  AstraZeneca

Cambridge CB2 0AA, , United Kingdom -

Start DateExpiry DateSalaryPosted OnExperienceSkillsTelecommuteSponsor Visa
Immediate23 Dec, 2024Not Specified27 Sep, 2024N/AImage Processing,3D ReconstructionNoNo
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Description:

ESSENTIAL REQUIREMENTS

  • Cryo-EM experience, including image processing with 3D reconstruction.
  • Strong desire to become an in situ structural biology expert

DESIRABLE REQUIREMENTS

  • Experience with focussed ion beam operation (FIB) and plasma FIB
  • Vitrification of cells
  • Experience in working in large, cross-disciplinary teams

Responsibilities:

WHAT YOU’LL DO

You will be an enthusiastic individual with a PhD in a relevant field, or due to complete within 6 months, with a strong background in cryo-EM, preferably with FIB experience.

KEY DUTIES & RESPONSIBILITIES:

  • Research, design and implement innovative preparation of cell lines for in situ structural biology of SARM1 by cryo-EM
  • Innovative high resolution data collection and image processing of in situ samples by 2D and 3D methods
  • Lead and drive the project under the supervision of Kasim Sader, Vijay Chandrasekar and Michael Grange
  • Plan, write, publish, and present high-quality scientific papers
  • Participate in function and department activities in AstraZeneca, learn about drug discovery and development processes and get exposure to new scientific advances


REQUIREMENT SUMMARY

Min:N/AMax:5.0 year(s)

Information Technology/IT

Pharma / Biotech / Healthcare / Medical / R&D

Software Engineering

Graduate

Proficient

1

Cambridge CB2 0AA, United Kingdom