Process Chemist

at  Lilly

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Position Summary: This individual will be experienced in synthetic organic chemistry with a preference for process chemistry expertise. The ideal candidate will be comfortable working independently in a laboratory setting, and have demonstrated abilities in modern organic synthesis, purification and characterization techniques. Familiarity with current Good Manufacturing Practice (cGMP), peptide synthesis and/or radiopharmaceutical precursor development would be considered assets. The candidate will be comfortable working both independently as well as in collaboration with other departments and external partners to ensure successful development of novel drug candidates in the RLT pipeline.

Key Accountabilities:

• Design and plan expedient synthetic routes based on literature precedent for compounds that are significant to RLT drug pipeline.
• Conduct and interpret a wide variety of modern chemical analyses including NMR, HPLC, and MS to elucidate chemical structure, stereochemistry, stability, and purity of synthesized compounds.
• Accurately record experiments and related data in accordance with Good Documentation Practices (GDocPs), either in hard copy or electronic formats.
• Provide verbal and written reports and presentations to company stakeholders and managers in a clear and concise manner.
• Support interdepartmental planning and development of the RLT pipeline.
• In collaboration with the direct manager, process chemistry team, project managers, and cross-functional teams, develop timelines and deliverables of chemical entities to accomplish project goals.
• Distribution of synthesized compounds to internal and external partners for downstream development activities in a timely manner.
• Work well in a fast-paced environment.
• Perform other duties as assigned

Basic Requirements:

• BSc/MSc with 3+ years of relevant industry experience in organic, organometallic, or process chemistry OR a PhD in a hands-on chemistry subdiscipline with 1+ years industry experience.
• In depth knowledge of and experience in current synthetic organic/organometallic methods.
• Demonstrated strong scientific and analytical skills required.
• Strong oral and written communication skills, and interpersonal skills.
• High attention to detail, well organized, and highly motivated.
• Excellent ability to multitask and prioritize workload.
• Excellent planning skills with the ability to work seamlessly as part of a team or independently.
• Proficient in MS 365 (Excel, Word, PowerPoint).
• Experience with chemical literature search tools (e.g. SciFinder, Reaxys, PubMed)

RESPONSIBILITIES:

• Independently perform complex and diverse organic syntheses, purifications, and characterizations.
• Understand the physical and chemical properties of products, raw materials, intermediates, and reagents, with the ability to select appropriate reaction conditions with reference to literature.
• Analyze technical data and documents, provide recommendations and planning for subsequent experiments.
• Support synthesis scale-up efforts and other technology transfer activities.
• Maintain a safe and functional laboratory environment including but not limited to equipment maintenance, chemical inventory, ordering and receiving chemicals and consumables.
• Ensuring adherence to local Environmental, Health and Safety (EH&S) regulations, company policies, standard laboratory safety practices and any other quality or regulatory requirements.

Key Accountabilities:

• Design and plan expedient synthetic routes based on literature precedent for compounds that are significant to RLT drug pipeline.
• Conduct and interpret a wide variety of modern chemical analyses including NMR, HPLC, and MS to elucidate chemical structure, stereochemistry, stability, and purity of synthesized compounds.
• Accurately record experiments and related data in accordance with Good Documentation Practices (GDocPs), either in hard copy or electronic formats.
• Provide verbal and written reports and presentations to company stakeholders and managers in a clear and concise manner.
• Support interdepartmental planning and development of the RLT pipeline.
• In collaboration with the direct manager, process chemistry team, project managers, and cross-functional teams, develop timelines and deliverables of chemical entities to accomplish project goals.
• Distribution of synthesized compounds to internal and external partners for downstream development activities in a timely manner.
• Work well in a fast-paced environment.
• Perform other duties as assigned.

Basic Requirements:

• BSc/MSc with 3+ years of relevant industry experience in organic, organometallic, or process chemistry OR a PhD in a hands-on chemistry subdiscipline with 1+ years industry experience.
• In depth knowledge of and experience in current synthetic organic/organometallic methods.
• Demonstrated strong scientific and analytical skills required.
• Strong oral and written communication skills, and interpersonal skills.
• High attention to detail, well organized, and highly motivated.
• Excellent ability to multitask and prioritize workload.
• Excellent planning skills with the ability to work seamlessly as part of a team or independently.
• Proficient in MS 365 (Excel, Word, PowerPoint).
• Experience with chemical literature search tools (e.g. SciFinder, Reaxys, PubMed).

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.

• To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions