Company Description
For 35 years, we have been developing cutting-edge science and technology to empower biomedical research and personalized medicine. We combine excellence from more than 60 disciplines in natural sciences, engineering, and informatics to make a significant contribution to biomedical sciences. We encourage a creative working environment driven by pioneering spirit – to seek new horizons – boldly envisioning the future and turning it into reality. Today, more than 4,700 experts from over 50 countries contribute to our sustainable success.

Job Description

• While obtaining your PhD, you will have the opportunity to join a dynamic team and develop solutions to improve gene therapy for hemoglobinopathies towards clinical translation.
• You will intensively work with human and murine hemopoietic stem cells that you genetically correct with several genetic tools (LNPs, electroporation, viral vectors etc). You will then characterize these modified cells for functionality in vitro using a wide panel of tools and technologies as well as in vivo.
• As you love to explore new approaches and develop new solutions, you will apply a broad spectrum of different methods including, primary hemopoietic cell culture and differentiation, culture of stable cells lines, immunophenotyping assays based on fluorescent cytometric cell analysis, etc. You will also help develop and use automated screening assays to accelerate your work.
• Molecular biology and gene therapy are your favorite topics and you are keen to apply your skills and knowledge of both topics synergistically.
• This position offers you the unique opportunity to obtain your PhD while developing new technologies and gaining scientific insights in a very dynamic field and gives you the chance to learn how ideas will translate into practice and become a therapy concept.
• Your workplace will be in Bergisch Gladbach.

QUALIFICATIONS

• You must not have resided or carried out your main activity (work, studies, etc.) in Germany for more than 12 months in the 36 months immediately before the start of your PhD. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account.
• You must not be in possession of a doctoral degree.
• You hold a Master’s degree (no PhD) in biomedical sciences, molecular biology, bioengineering, biotechnology, pharmacy or a related field, or an MD.
• You are passionate about life sciences and biomedicine, and want to achieve a PhD degree on the topic described in the description above.
• You are experienced with molecular biology technics and with (primary) cell culture and capable of working with novel devices (e.g. Flow cytometers).
• Preferably, you are familiar with functional testing of primary human cells and highly interested in performing in vivo experiments using mouse models.
• You are ambitious, well organized, and have excellent communication skills.
• You are proficient in English both spoken and written.
• You have a solutions-oriented mindset that thrives in a multidisciplinary team.
• You have the ability to work independently and have a critical mindset.
• You are an enthusiastic and motivated person, eager to participate in network-wide training events, international travel, and public awareness activities.
• Willingness to travel
• You are a team player and interested to work in interdisciplinary teams.
• You have not carried out work.

SKILLS AND EXPERTISE THAT ARE VIEWED AS AN ASSET:

• Knowledge and experience in gene therapies, translational research, immunology, and regenerative medicine
• Experience in advanced microscopy and mass spectrometry
• Experience in GLP, animal and lung models
• Experience in omics methods, data analysis, and interpretation
  Additional Information
  The position as PhD fellow is full time and lasts 3 years.

Please refer the Job description for details