R4 -Senior Scientist

at  Pfizer

JOB DESCRIPTION

1. General Information:
   Job Title: Senior Scientist, Antibody Engineering
   Department: BioMedicine Design
   Position Reports to: PRD & ORD BioTx
2. Job Purpose: Antibody engineering and screening sciences within a nimble (multi-project) and cutting-edge biotherapeutic discovery team in our Protein Discovery and Optimization Group. Our laboratory is located at Grange Castle in Dublin, Ireland and focuses on the application of advanced protein engineering technologies towards the discovery and optimization of novel protein therapeutics, with a particular emphasis on monoclonal antibodies. Pfizer is a leader in the development of protein biopharmaceuticals and has a successful track record of multiple product approvals in cancer and inflammatory diseases. This is an exciting opportunity to join a team in a world-class organisation dedicated to the application of industry-leading science for treatment of significant unmet medical needs. Applicants for this position should clearly highlight their relevant experience and qualifications which make them directly suited to this role.

3. Senior Scientist
   Reporting Structure: Report to Research Group Leader

4. Job Responsibilities:

• Perform world-class antibody discovery & optimisation work (including phage and yeast display technologies, library construction, selection, screening and sequencing) within a team of researchers addressing the business requirements of BMD.
• Provide technical support in protein engineering for drug discovery, across functions.
• Perform trouble-shooting and resolution of experimental issues.
• Mentor technical training in key technology areas for group members, where needed.
• Author reports, publications and technical manuals for lab experimental procedures.
• Facilitate cross-functional project teams internally within the local team, across BMD and between BMD and WRD research units (RUs).
• Implement effective technology improvement processes by which optimised scientific and technological solutions are provided to BMD and the RUs.
• Develop and maintain productive links with colleagues in BMD and across WRD, to maintain up to date information, skills and knowledge base for the team.
• The role may evolve to include project leadership

1. Education/Experience

• Minimum qualification BSc & PhD degree in Biochemistry, Biotechnology, Molecular biology or equivalent discipline.
• Three years’ experience in a biotechnology/biochemistry research environment is preferred.
• Experience in working on key roles in biotherapeutic drug discovery projects is preferred but not essential.
• Proven experience in protein engineering and/or therapeutic antibody discovery is preferred but not essential.
• Functional knowledge and experience of protein display technologies and the use of recombinant antibody libraries is strongly preferred.
• Proven hands-on experience with display technologies.
• Proven ability to organise and conduct therapeutic antibody display discovery campaigns.
• Any experience with project or people management should be highlighted.

Work Location Assignment: On Premise

Additional Information

• In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.
• Please note there is no relocation support available for this position

How to apply

• Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you!

Purpose
Breakthroughs that change patients’ lives… At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.
Digital Transformation Strategy
One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.
Equal Employment Opportunity
We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.
Disability Inclusion
Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!
Research and Development

• Perform world-class antibody discovery & optimisation work (including phage and yeast display technologies, library construction, selection, screening and sequencing) within a team of researchers addressing the business requirements of BMD.
• Provide technical support in protein engineering for drug discovery, across functions.
• Perform trouble-shooting and resolution of experimental issues.
• Mentor technical training in key technology areas for group members, where needed.
• Author reports, publications and technical manuals for lab experimental procedures.
• Facilitate cross-functional project teams internally within the local team, across BMD and between BMD and WRD research units (RUs).
• Implement effective technology improvement processes by which optimised scientific and technological solutions are provided to BMD and the RUs.
• Develop and maintain productive links with colleagues in BMD and across WRD, to maintain up to date information, skills and knowledge base for the team.
• The role may evolve to include project leadershi