Research Assistant

at  Imperial College London

AVAILABLE DOCUMENTS

Attached documents are available under links. Clicking a document link will initialize its download.

• Download: Employee Benefits Booklet.Pdf
• Download: Research Assistant In Speckled Protein Job Description.Pdf

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.
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ABOUT THE ROLE

We are looking for a Graduate Research Assistant for 2½ years, to study proteins that sense and suppress infection by DNA viruses. You will use a combination of classical and cutting edge techniques in protein biochemistry, cell biology, classical virology, microscopy and genomics assays, particularly in the context of Epstein-Barr virus infection of B cells, and Herpes Simplex virus infection of primary fibroblasts.

WHAT YOU WOULD BE DOING

In this role you will:

• work as part of a small team studying how the SAND domain of speckled proteins (the Sp100 family) binds DNA, to test whether this allows cells to sense and suppress viral DNA in the nucleus.
• assist with the day to-day planning, development, running and analysis of assays, including biochemistry (protein purification, DNA-binding assays, and antibody validation), infection assays (plaque assay, luciferase assays), and cell-based assays for protein interaction studies (e.g. FRET and fluorescence microscopy) and genomics assays (transcriptomics, ATAC-seq and ChIP), according to your skills and aptitudes.
• Present your findings to colleagues and contribute to the writing of reports
• Assist in the training and development of other staff and students in the research group.
• Contribute to the smooth running of the lab.