Research Assistant in Biological Activity of Natural Products

at  Cardiff University

MAIN FUNCTION

To contribute to research within the area of chemical signalling between insects and plants, principally involving isolation of biological samples and determining biological activity, carrying out supporting work that helps lead to the publishing of high-quality research. To pursue excellence in research and to inspire others to do the same

PROJECT DESCRIPTION

The project comprises a new multidisciplinary programme and is collaborative with other scientists beyond the School of Chemistry. In order to identify natural chemical signals effecting long range mosquito attraction, the work will centre on the identification and provision of volatile components of flowering plants as sugar sources for these insects. Samples of volatiles will be entrained from air on porous polymers and the volatile samples eluted with purified solvents for analysis by gas chromatography (GC). Compounds giving GC peaks, associated with bioactivity established by collaborators on the project, will be tentatively identified by GC coupled mass spectrometry (GC-MS) Further chemical analytical techniques will confirm structures by use of spectroscopically authenticated compounds from synthesis and sustainable natural sources. The compounds will be used in confirming the bioactivity as new mosquito attractants. These attractants will be employed in the development of lure and kill strategies against mosquito vectors of pathogens, specifically those causing malaria, in association with emerging commercial and international partners.

Research

• To undertake research within the area of chemical signalling between insects and plants, specifically the attraction of mosquitoes by volatile compounds associated with feeding on floral nectar, by planning, preparing, setting up, conducting and recording the outcome of experiments;
• Actively participate within the research group, communicating and presenting research at meetings, through publications and other recognised avenues as appropriate, ensuring information is communicated to internal and external partners
• To contribute and support research publications and presentations as required;
• To contribute and support research funding bids as required;
• To analyse and communicate complex ideas, concepts and data using appropriate methods and packages;To resolve issues and support colleagues in devising procedures required to ensure accurate and timely reporting;
• To generate research output and contribute to the development of independent and original ideas as appropriate;
• To provide support in research activities for undergraduate courses and research programmes and provide guidance to other members of staff within the research team;
• To maintain and update area of specialist knowledge, researching and critically appraising relevant literature within the area.

Other

• To participate in School administration and activities to promote the School and its work to the wider University and the outside world;
• To undergo personal and professional development that is appropriate to and which will enhance performance;
• To ensure that an understanding of the importance of confidentiality is applied when undertaking all duties;
• To abide by the University policies on Health and Safety and Equality, Diversity & Inclusion;
• Any other duties not included above, but consistent with the role