Research Associate I, Antibody Engineering

at  Twist Bioscience

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and to create in-vivo diagnostics that alert us when we are sick, and many more applications.
We are seeking an outstanding, innovative, and creative Research Associate to join our antibody discovery effort. This research associate will play multiple roles within the Biopharma group and will work within a team responsible for antibody discovery utilizing in vitro display technologies, e.g. phage display, ribosome display, and yeast display.

• Perform phage display library panning for both soluble protein and cell membrane targets
• Execute kinetic studies of antibody-antigen interactions using surface plasmon resonance (SPR) instrumentation
• Assist with library construction using various molecular cloning skills like PCR, restriction digestion, ligation, DNA gel purification, and transformation
• Run DNA sequencing by NGS and prep samples for Sanger sequencing, summarize sequencing results and be able to design necessary sequencing primers
• Record experimental findings and present to supervisor, in group meetings, and other stakeholders
• Perform high throughput primary ELISA binding assays with the help of automation
• Work collaboratively under aggressive timelines
• Must be able to work as an individual contributor and as a team