Research Associate I, Bioconjugation

at  Zymeworks Inc

COMPANY DESCRIPTION

Zymeworks is a publicly listed (NASDAQ:ZYME) R&D and clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation, bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates. We are a global company headquartered in Vancouver, BC, with operations in Bellevue, WA, Dublin, Ireland, Singapore and Redwood City, CA.

• Performs multistep bioconjugation experiments to generate antibody and protein conjugates (milligram to gram scales) for in vitro and in vivo evaluation.
• Applies modern analytical techniques to characterize the biophysical properties and stability of proteins and protein-conjugates.
• Proposes and executes technology development efforts to advance techniques related to antibody drug conjugate (ADC) design, preparation and characterization.
• Documents raw and analyzed data. Collaborates with colleagues to interpret results and design follow-up experiments.
• Prepares written reports for internal and external use; makes presentations to team and department regularly.
• Seeks to understand ongoing developments and innovations in ADCs through attention to scientific literature and internally generated data.
• Adheres to Zymeworks standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
• Maintains a safe, organized, and operational lab.
• Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks’ policies and practices.
• Actively works to foster an environment of effective and collaborative working relationships across the organization.