Research Associate II - Sequencing and Molecular Biology

at  AlivaMab Discovery Services

Overview:
AlivaMab Biologics is seeking an outstanding individual to join the Antibody Engineering Team. The successful applicant will have the responsibility to support antibody discovery and engineering projects through Next-Generation Sequencing (NGS) of various samples including, but not limited to, hybridomas, single B-cells, immune repertoires, and phage libraries. The individual will also perform molecular cloning and contribute to technology development in the Molecular Biology group. This position will report to the Principal Scientist, Sequencing and Molecular Biology, and work closely with scientists in the Protein Sciences and Antibody Discovery teams.
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners’ design goals, from simple to extraordinarily challenging, through collaborative access to our scientists’ creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics, and developability, with expanding capabilities for engineering advanced modalities, including multispecifics, single-domain human VH antibodies, and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
Responsibilities:

QUALIFICATIONS

• BS in Molecular Biology, Biomedical Engineering, or a related scientific field with a minimum of 3 years of relevant industry experience; or MS degree with 1-3 years of experience.
• Experience with NGS workflows and sequencing
• Experience with molecular cloning is preferred
• Ability to improve and streamline existing processes
• Operationally minded with ability to summarize and track workflow status and performance
• Highly organized including time management, planning, and documentation
• Self-motivated with the ability to work with and support multiple groups across the organization
• Experience using electronic lab notebook services (specifically Benchling is a plus).
• Prior experience in Bioinformatics and automation is a plus

• Execute NGS workflow from sample submission to sequencing analysis
• Perform data analyses and report generation (bioinformatics experience is a plus)
• Further optimize NGS workflow, troubleshoot when needed, and identify areas for improvement
• Work in close collaboration with stakeholders and project managers to address operational needs
• Document the work promptly and accurately using Electronic Lab Notebook and generate protocols and SOPs
• Manage and maintain operation inventory and lab supply
• Keep up with routine maintenance of NGS and other lab instruments
  Qualifications: