Research Associate in Genomics

at  Roche

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.
The Position
In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
360 Labs Initiative at a Glance
The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio.
Operating as an integrated ecosystem, the 360 Lab environment will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing and learning experiences in close collaboration with our therapeutic areas and functions. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities.
We are currently recruiting scientific professionals with varied backgrounds in Flow Cytometry, Genomics, Proteomics, Histopathology and Microscopy / Imaging. In these new roles, your collaborative mindset is as valued as your scientific expertise. The 360 Labs are by nature a hands-on, interactive workplace where face to face presence in our labs is a priority. Our ambition is to bring to life a thriving workplace environment, acting as an highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability.
Job Mission and Impact
The Genomics Core Technology Platform within the 360 Labs Initiative is seeking to expand its team with experienced, highly motivated, collaborative, and customer-centric Research Associates. We are looking for individuals who are passionate about utilizing both bulk and/or single-cell Next Generation Sequencing (NGS) technologies in early drug discovery projects. The ideal candidates will have a strong background in the life sciences and demonstrated technical and scientific expertise in advanced bulk and/or single-cell NGS methodologies. You will work with urgency as part of a matrix team, collaborating with experts across various therapeutic disease areas and functions to drive drug discovery projects forward. Additionally, you will contribute to the ongoing development of the Genomics Core Technology Platform within the pRED organization.

Your Role and Responsibilities

• You will plan, design and execute experiments, to develop, optimize and validate both routine and customized bulk and/or single cell NGS approaches, as well as identifying and resolving technical challenges associated with diverse NGS workflows;
• You will ensure the continued production of high-quality research data by performing regular quality control of NGS data and troubleshooting of related NGS instrumentation;
• You will embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies /approaches in the genomics field.

Your Profile

• You hold a Master’s degree in Biology, Biochemistry, Molecular Biology, or a related field, with at least 3-5 years of professional experience focused on bulk and/or single-cell NGS methods, ideally within a genomics core facility, either in the pharmaceutical industry or academia.
• You possess proven, hands-on practical experience in carrying out diverse NGS workflows, including, but not limited to, single-cell dissociation, RNA/DNA extraction, library preparation, and sequencing. Candidates with expertise with 10X Genomics 3’, 5’, and FLEX technologies, as well as in the operation of NGS platforms, both Illumina and Oxford Nanopore, are highly desired;
• You are familiar with the software, tools and resources commonly used for quality control, storage and analysis of NGS data.

In addition to your professional expertise and critical technical skills we are looking for candidates who:

• Are resourceful and flexible in problem solving, have excellent organizational skills, and are able to work in a matrix environment with a sense of urgency in a fair, open and collaborative manner, ensuring that everyone has the required information at all times;
• Can think outside the box and work in diverse, multicultural, global teams, with a demonstrated ability to implement new ideas in fast-paced research environments
• Bring excellent written communication and presentation skills with a high fluency in English.

Your Location
This position is based in Basel.
Our commitment
Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

• You will plan, design and execute experiments, to develop, optimize and validate both routine and customized bulk and/or single cell NGS approaches, as well as identifying and resolving technical challenges associated with diverse NGS workflows;
• You will ensure the continued production of high-quality research data by performing regular quality control of NGS data and troubleshooting of related NGS instrumentation;
• You will embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies /approaches in the genomics field