Research Associate in the Department of Basic & Clinical Neuroscience

at  Kings College London

Job id: 097285. Salary: £44,105 per annum, including London Weighting Allowance.
Posted: 18 October 2024. Closing date: 23 October 2024.
Business unit: IoPPN. Department: Basic & Clinical Neuroscience.
Contact details: Professor Jernej Ule. Jernej.ule@kcl.ac.uk
Location: Denmark Hill Campus. Category: Research.
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About us
This post is based within the UK Dementia Research Institute (DRI) centre that is embedded within the Department of Basic and Clinical Neuroscience at King’s College London www.kcl.ac.uk/ioppn/depts/bcn/dri/lab-groups
The UK DRI is focused on cutting-edge dementia research funded by the Medical Research Council (www.ukdri.co.uk)
About the role
Professor Jernje Ule is seeking to appoint two enthusiastic and organised research associates to his research group working on the mechanisms of amyotrophic lateral sclerosis caused by mutations in RNA binding proteins. The group focuses on transcriptomic approaches to study RNP assembly and its defects in disease.You will contribute to the project by studying RNA condensates that contribute to the regulation of gene expression by;
Using methods such as transcriptomics, proteomics and imaging
Establishing new techniques
Producing relevant publications.
The Ule Lab is highly collaborative. You will join a multidisciplinary team on the Denmark Hill Campus with a leading role in:
Designing and performing experiments
Developing technical advances
Performing data analysis
resenting the results
Writing up manuscripts to be submitted to peer-review journals
You will be given opportunities to work closely with a broad range of other scientists across the UK DRI.
King’s College also encourages continued professional development of its staff through both internal and external educational courses covering skills such as project, financial or time management and communication, as well as scientific topics.
The posts will be offered on an a fixed-term contract for 1 year.
About you
To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

• PhD awarded in Molecular Biology or a related discipline
• Experience in molecular biology and transcriptomics
• Advanced experience in cell biology, neuronal differentiation and advanced imaging
• Experience in establishment of new methods
• Excellent oral and written communication skills
• Excellent organizational, interpersonal and problem-solving skills.

Desirable criteria

• Experience with proximity proteomics
• Experience with single-molecule RNA imaging.
• Experience with computational analyses of transcriptomic, proteomic and/or imaging data

Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.
Further information
We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.
We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King’s.
We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.
To find out how our managers review your application, please take a look at our ‘How we Recruit’ pages.
This role does meet the requirements of the Home Office and therefore we are able to offer sponsorship for candidates who require the right to work in the UK.
This post is subject to an Occupational Health clearance.

Please refer the Job description for details