RESEARCH FELLOW

at  University of Michigan

Ann Arbor, MI 48109, USA -

Start DateExpiry DateSalaryPosted OnExperienceSkillsTelecommuteSponsor Visa
Immediate22 Jan, 2025Not Specified23 Oct, 2024N/AChemistryNoNo
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Description:

MISSION STATEMENT

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

REQUIRED QUALIFICATIONS*

Ph.D and a background in Chemistry.

Responsibilities:

Work will be done with an NIH funded project on development novel PAPP-A inhibitors and compounds targeting protein-protein interactions involved in regulating programmed cell death, apoptosis. In this position, you will be involved in designing, synthesis, optimizing synthetic process and characterization of novel synthesized small-molecule inhibitors with various analytical and preparative techniques including thin-layer chromatography, column chromatography, HPLC, NMR, LC-MS, IR, recrystallization. You will be also involved and have responsibilities on managing hazardous waste, organize chemical inventory, and searching scientific databases (Scifinder). In this position, as part of the multidisciplinary team in my laboratory, you will have an opportunity to gain expertise in medicinal chemistry, structural biology, biochemical and cell-based assays, towards discovery, development and characterization of biological active compounds as potential therapeutics. As your work progresses, there will be fruitful opportunities for you to be involved with other projects, for example developing small-molecule inhibitors targeting epigenetics.


REQUIREMENT SUMMARY

Min:N/AMax:5.0 year(s)

Hospital/Health Care

Pharma / Biotech / Healthcare / Medical / R&D

Health Care

Graduate

Proficient

1

Ann Arbor, MI 48109, USA