Research Scientist (DSP)

at  LGC Clinical Diagnostics

Company Description
LGC’s Clinical Diagnostics Business Unit develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions and component materials for the extended life sciences industry. We partner with IVD assay developers, and pharmaceutical, CRO and academic institutions in commercialization activities across the entire diagnostic pipeline - from concept and early-stage research, through expedited product development and onwards into routine clinical use. Laboratorians and diagnostic professionals across disciplines of clinical chemistry, immunochemistry, serology, molecular diagnostics and clinical genomics rely on LGC’s products to support accurate and reliable diagnostic results.
Our operating entities include The Native Antigen Company, which is a manufacturer and supplier of antigens and antibodies, which are key components in vaccine research, and for the accurate diagnosis of a wide range of infectious diseases. Our customer base includes key Pharmaceutical and IVD companies, in addition to the academic sector and a wide range of Biotechnology companies. Alongside The Native Antigen Company, the Clinical Diagnostics Business Unit also includes SeraCare Life Sciences, Maine Standards Company and Technopath, which are in vitro diagnostics (IVD) manufacturers of quality measurement tools (calibrators, controls, linearity, EQA/PT, biological materials). Our 450+ employees operate an ISO 9001-accredited facility in Oxford, UK, and FDA-registered and ISO 13485-accredited facilities in Maine, Massachusetts and Maryland, USA, and Tipperary, Ireland.
Each day, our world-class staff, scientific expertise, operational efficiency and superior quality systems are ready to support the range of advanced technologies that collectively improve patient outcomes - from the widely adopted and established through to cutting-edge NGS and precision diagnostics.

Job Description

• Job Purpose

The role of the Research Scientist is to develop purification strategies for biomolecules such as proteins. The Research Scientist is expected to trouble-shoot problems, devise alternative strategies and protocols, and to instruct and train Junior Research Scientists.

QUALIFICATIONS

• Science-based degree (or similar relevant work experience)
• Previous experience with AKTA chromatography systems and Unicorn software is required
• Proven experience working in a scientific environment (Master’s degree or similar research projects in industry)
• High accuracy and attention to detail
• Ability to follow and maintain SOPs
• Good verbal and written communication standards to allow clear lines of communication within the R&D team
• Experience using basic IT programs, primarily Microsoft Excel, PowerPoint, and Word
• Desire to support other team members when required to help the overall business function
  Additional Information
  All your information will be kept confidential according to EEO guidelines

• Developing protein purification protocols using AKTA chromatography systems as part of the Downstream Process Development Team
• Writing SOPs and supporting documents for those protocols
• Day-by-day reporting of results to and discussion of experimental strategies with the Lead Development Scientist as requested
• Preparing buffers and other lab materials
• Analysing proteins using SDS-PAGE, Western blot, ELISA
• Maintaining appropriate stock levels of high-turnover research materials
• Meticulous note-keeping of research activities is essential
• Following SOPs and instructions of senior members of the R&D team
• Liaise with Production Team and Upstream Development Team where necessary to ensure research material supplies are ready for experiments
• Weekly meetings with supervisor to keep clear lines of communications within the R&D team
• Attendance of weekly R&D meetings
• Additional duties as required by Senior R&D staff
• Literature Reviews
• Trouble shooting problems within the R&D team
• Supporting, leading and training junior members as required