JOB DESCRIPTION

The Research Scientist will design and execute biomarker and translational strategy for the clinical development of Kite’s chimeric antigen receptor (CAR-T) programs in Multiple Myeloma. As a member of the Translational Medicine Clinical Pharmacology team, you will be at the intersection of Research and Clinical Development, providing valuable insight into the function of CAR-T cells in patients and the development of potential prognostic tools. You will facilitate clinical trial execution, synthesize scientific data, communicate key findings cross-functionally.

BASIC QUALIFICATIONS

Doctorate and 2+ years of scientific experience
OR
Master’s and 6+ years of scientific experience
OR
Bachelor’s and 8+ years of scientific experience

PREFERRED QUALIFICATIONS

• Familiarity and experience with clinical and biomarker operations
• Prior experience in Regulatory filings
• Deep background in cancer immunotherapy, immunology and/or oncology with experience focusing on Multiple Myeloma
• In-depth understanding of multiple myeloma, knowledge of clinical landscape, evolving therapy, competitive scenarios
• Excellent understanding of clinical, translational, and mechanistic data
• Understanding of early or late-stage drug and translational development process; including clinical trial experience in industry or academia
• Familiarity with bioanalytical assay development and validation in a GxP environment
• Experience working with engineered T cells, immunophenotyping, and NGS-based approaches to profile the function of tumor and immune cells
• Comfortable in a matrixed and fast-paced company environment and able to adapt to changing priorities
• Meaningful collaboration, excellent interpersonal and communication skills
• Proficient with data presentations to communicate to a diverse cross-functional audience
• Maintain a high degree of accuracy and attention to detail
• Ph.D. degree in biology-related field (immunology, cancer biology, bioinformatics or a closely related field)
  The work you do at Kite will help change how cancer is treated and ensure patients and their families have more time together. Ready to create more tomorrows with us? Hit apply.
  

  LI-ML1

• Directs and establishes pharmacokinetic and pharmacodynamic (PK/PD) analysis to support clinical pharmacology for CAR T clinical trials in Multiple Myeloma
• Serves as Biomarker lead on clinical study teams to oversee delivery of pharmacology data and documentation required for pivotal and registrational study filings
• Reviews and contributes to clinical protocol design and study activities
• Identifies and establishes agreements with contract research organizations (CRO) and support the transfer of novel methods
• Collaborates with Clinical development teams including Clinical Operations, Regulatory, Clinical Data Management and Biometrics/Stats to advance data acquisition and analyses of clinical trial data
• Guides the resolution of clinical pharmacology/translational queries from regulatory agencies, supports writing and reviewing responses to regulatory queries.
• Supports the preparation of data packages for publication with medical writers, presentation and/or submission to regulatory agencies
• Collaborates with Bioinformatics and Statistical teams for exploratory biomarker correlative studies and deeper analysis of tumor biology and CAR T functionality
• Contributes to external scientific discussions/research collaborations and publications and engagement with key opinion leaders in the field