Scientist - Analytical Sciences

at  OXGENE

Overview:
The Scientist in Analytical sciences will contribute to internal platform development and commercial projects, focused on advancing the delivery of our customers new therapeutics. They will be expected to drive the design, optimisation and execution of analytical assays, ensuring the accurate quantification and characterisation of viral therapy products. They will perform and interpret accurate data analysis in line with customer specifications and generate high-quality analytical data summaries suitable for presentation to clients. They will collaborate with cross-function teams, including research teams, process development, and quality control, plus teams at other company sites, to ensure alignment of analytical strategies and protocols. In performing their duties, the Scientist will also provide support for; lab maintenance (cleaning, stock management and reference materials), quality management (recording results and updating forms and SOPs), and communication (presenting work in meetings).

Responsibilities:

• Work closely with Senior Scientist colleagues to define objectives, and key support required for lab functions.
• Titration, characterisation and safety testing of viral vector material within planned timeframes.
• Troubleshooting and analysing experimental results and using this analysis to make suitable recommendations to project plans.
• Making recommendations for optimising procedures and processes, plus supporting the onboarding of new processes, with a focus on data integrity and accuracy.
• Supporting the alignment of analytical protocols across the different WuXi sites by carrying out cross-site optimisation experiments.
• Providing experimental analysis and project summaries for use in commercial reports.
• Complying with the company’s Quality Management Systems and writing SOP’s for established protocols and method development.
• Maintaining laboratory cleanliness to OXGENE standards, ensure laboratory equipment maintenance, safe working practices and general housekeeping.
• Presenting technical information, including analysis/results of experiments, to technical and non-technical audiences, both inside and outside the company
• Supporting other areas of Process Development as required with flexibility for additional training.
• Keeping up to date with relevant scientific literature and developments, appropriate to team projects and priorities.
• Supervising less experienced members of the team and supporting their training and development

Qualifications:

Essential Criteria:

• Minimum BSc in relevant scientific discipline (biology, chemistry), with relevant laboratory experience
• Ability to work in a laboratory independently and as part of a team on multiple projects, following established protocols, SOPs and safety procedures.
• Practical experience of some or all techniques used in biopharmaceutical analysis (aseptic handling, mammalian cell culture (suspension and adherent), qPCR, ddPCR, ELISA, flow cytometry, microscopy). qPCR/ ddPCR and cell transduction assays are likely to be of particular importance within the role.
• Excellent attention to details, good time management, communication, teamwork and numeracy skills
• Experience with accurate and diligent documentation of work, reagent preparation and sample tracking, preferably within an electronic system (ELN/LIMS)
• Basic proficiency in MS office package (Excel, Word). Intermediate or advanced proficiency advantageous

• Work closely with Senior Scientist colleagues to define objectives, and key support required for lab functions.
• Titration, characterisation and safety testing of viral vector material within planned timeframes.
• Troubleshooting and analysing experimental results and using this analysis to make suitable recommendations to project plans.
• Making recommendations for optimising procedures and processes, plus supporting the onboarding of new processes, with a focus on data integrity and accuracy.
• Supporting the alignment of analytical protocols across the different WuXi sites by carrying out cross-site optimisation experiments.
• Providing experimental analysis and project summaries for use in commercial reports.
• Complying with the company’s Quality Management Systems and writing SOP’s for established protocols and method development.
• Maintaining laboratory cleanliness to OXGENE standards, ensure laboratory equipment maintenance, safe working practices and general housekeeping.
• Presenting technical information, including analysis/results of experiments, to technical and non-technical audiences, both inside and outside the company
• Supporting other areas of Process Development as required with flexibility for additional training.
• Keeping up to date with relevant scientific literature and developments, appropriate to team projects and priorities.
• Supervising less experienced members of the team and supporting their training and developmen