Scientist

at  CAMRIS

Overview:
We are seeking a Scientist to support the National Institutes of Health’s (NIH), world renowned National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a preeminent team focused on positively impacting millions of lives around the world with groundbreaking research. Candidates will work at a prominent, diverse and vibrant NIAID worksite to directly support exciting ongoing research activities as a contractor team member. Accelerate your career and apply below to help us make a difference.
CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today’s most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.
Our employees enjoy a diverse, collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities:

• Assist the Federal Task Leader (FTL) to ensure the scientific rigor for immunoassay and broader scope of analytical assays.
• Collaborate with scientists in other departments from upstream, downstream and formulation development groups to provide assay support and optimize analytical assays.
• Author experimental plan (EP), lead and carry out new method development and characterization plan, trouble shoot, execute, and coordinate experiments that will lead to conclusions.
• Write technical reports and manuscripts with scientific rigor. Write one or more per year reporting new scientific advancement.
• Identify scientific gaps in current project and provide recommendations to the FTL for correction.
• Work independently within project teams to design, develop and optimize analytical assays and provide assay support for clinical trial vaccine candidates. Write SOPs and publications if method is deemed innovative by FTL.
• Reports to FTL weekly with progress and data packages. Bring assessment with suggestions, and target timelines. Thoroughly and accurately communicate scientific rationale and findings to VPP leadership.
• Design and execution of experiments for the development of analytical assays required for product development and clinical manufacturing.
• Lead experimental design, carry out experiments, trouble shoot methods or help with trouble shooting material issues with solid methods.
• Write and review technical protocols and reports documenting analytical development studies pertaining to his/her work and the work of the group.

Qualifications:

• PhD in biochemistry or an immunologist or related discipline with relevant years of experience and capabilities.
• 10+ years in a related scientific discipline.
• Have in-depth institutional knowledge on clinical development products including all VPP monoclonal antibodies, recombinant proteins for vaccine candidates, including virus-like particles (VLP) and nanoparticles.
• Demonstrated analytical capabilities with techniques used in the analytical development in support of process and product development may include:
• Binding assays.
• Cell based assay.
• Residual immunoassays.
• A thorough understanding of protein analysis with experience in quantitative and qualitative protein analysis for assay development is required. Knowledge of the requirements and experience developing, qualifying and/or validating assays for cGMP products and managing method transfers between laboratories is highly desirable. The candidate will be involved in developing, characterizing, and transferring assays to the VRC pilot plant’s QC group for product release.
• Demonstrate the ability to work well within a team, the candidate must be a team player who can effectively work with other research, development, and cGMP personnel.

CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at www.CAMRIS.com. CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.
Some positions or sites may require that the incumbent be fully vaccinated against COVID-19. Proof of vaccination may be required.
Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding

• Assist the Federal Task Leader (FTL) to ensure the scientific rigor for immunoassay and broader scope of analytical assays.
• Collaborate with scientists in other departments from upstream, downstream and formulation development groups to provide assay support and optimize analytical assays.
• Author experimental plan (EP), lead and carry out new method development and characterization plan, trouble shoot, execute, and coordinate experiments that will lead to conclusions.
• Write technical reports and manuscripts with scientific rigor. Write one or more per year reporting new scientific advancement.
• Identify scientific gaps in current project and provide recommendations to the FTL for correction.
• Work independently within project teams to design, develop and optimize analytical assays and provide assay support for clinical trial vaccine candidates. Write SOPs and publications if method is deemed innovative by FTL.
• Reports to FTL weekly with progress and data packages. Bring assessment with suggestions, and target timelines. Thoroughly and accurately communicate scientific rationale and findings to VPP leadership.
• Design and execution of experiments for the development of analytical assays required for product development and clinical manufacturing.
• Lead experimental design, carry out experiments, trouble shoot methods or help with trouble shooting material issues with solid methods.
• Write and review technical protocols and reports documenting analytical development studies pertaining to his/her work and the work of the group