Scientist I - Healthy Aging

at  Harvard University

ABOUT US:

The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products that solve big problems. We support research that universities, companies, and venture capital firms don’t fund because they view it as too risky. We prefer to use the word “challenging,” and we love challenges. For more information discover our technologies, catch up on our recent news, or watch our latest videos.

DESIRABLE SKILLS:

• PhD in Biology and Biomedical Sciences or related strongly preferred
• Experience with the design, testing, and optimization of nucleic acid therapeutics is strongly preferred.
• Expertise in with LNP-mRNA in vivo studies is strongly preferred
• Expertise in cell state conversion for therapeutic applications is strongly preferred
• Strong understanding of fundamental concepts in cell state transitions and mRNA therapeutics is preferred
• Experience with Python or R is preferred Experience in authoring and critically reviewing technical documents, study protocols and reports related to mRNA therapy development, qualification, validation, and pre-clinical sample testing a plus.
• Excellent written and verbal communication skills, documentation skills and attention to detail, with the proven ability to work effectively as a member of a multidisciplinary team
• Full time post graduate industry experience with a focus on product development is preferred.

ABOUT THE ROLE:

We are looking for an innovative Scientist to join the Ichor Institute Project Team as the primary member of the research and development team responsible for generating the scientific and technical results to support a commercialization end-point. Reporting to the Director, Synthetic Biology and collaborating closely with other Ichor project team members, faculty, and Wyss Business Development, you will help drive the scientific program forward, in accordance with the agreed-upon project goals and timelines. As a translational institute and member of our Advanced Technology Team, you will be collaborating with various project teams and exposed to many different technologies in areas ranging from therapeutics and diagnostics to synthetic biology and materials science. You may also have the unique opportunity to transition into a newly formed start-up company.

WHAT YOU’LL DO:

• Design and execute experimental techniques related to identification and activation of genes related cellular aging.
• Formulate, test, and analyze data from mRNA-based compounds in coordination with CRO to evaluate metrics including dosage, timing, and toxicity.
• Present key results at group meetings, to project teams, and to stakeholders.
• Contribute to internal reports, scientific publications, and intellectual property filings
• Demonstrate a commitment to diversity, inclusion and cultural awareness through interactions and communications with others.
• Actively supports and collaborates with other areas of the Synthetic Biology platform and the Advanced Technology Team as it relates to new technology development, community building, administrative efficiencies, and operational protocols.
• Demonstrate a commitment to the Wyss Institute’s community values of courage, collaboration, innovation, impact, diversity, and respect through actions, interactions, and communications with others