Scientist III, Process Sciences

at  Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them.

EDUCATION

• BS or MS in biological sciences or engineering field
• Equivalent combinations of education, training, and relevant work experience may be considered

EXPERIENCE

• 5+ years of relevant cGMP experience in a manufacturing pharmaceutical/biotech environment or related areas
• Cell therapy automation technologies, closed system culture vessels, cell washers, cell separation technologies for autologous/allogenic product manipulation
• Experience in process development or manufacturing setting is helpful
• Aseptic cell culture processing (T cells, NK cells, CAR-T, or Stem Cells) in ISO 5 biosafety cabinets while using universal precautions for handling of human-derived materials preferred
• Experience in viral or non-viral genetic modification is helpful

KNOWLEDGE, SKILLS AND ABILITIES

• Understanding ‘why’ and not just the ‘how’ of processes and practices
• Ability to drive safety, quality, functional, technical and operational excellence
• Ability to work within cross functional teams and provide governance on project teams
• Cell culture and aseptic techniques
• Proven understanding of cGMP practices
• Effective written, interpersonal, and presentation skills.
• Excellent MS Office skills
• Ability to travel up to 20%
  Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory at Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.

• Lead process development and optimization activities associated with autologous and allogeneic cell therapy workflows with the aim to improve costs, speed, and quality of the product
• Work with blood cells or stem cells and routinely perform cell selection and activation, engineering (viral and non-viral), expansion, and cryopreservation
• Design experiments, analyze data and present data to internal and external collaborators or customers
• Serve as a process development subject matter expert to tackle technical challenges and support laboratory investigations
• Participate in customer core teams as the technical lead for that project
• Handle all project-related activities including the availability and suitability of materials and equipment to complete their assignments; coordinating hand-off of samples for downstream process and/or testing; Maintain accurate and detailed laboratory notes
• Contribute to the development of closed automated platforms that will be used for cell therapy manufacturing
• Work closely with clients for technology transfer activities, and with MS&T and Operations teams to transfer optimized process for clinical manufacturing and play a significant role in to trouble-shooting process challenges.
• Plan and implement resolutions to technical problems/issues
• Serves as a technical resource for junior staff and apply expertise in laboratory technology as a functional resource/trainer.