Scientist III, Research & Development

at  Thermo Fisher Scientific

SCIENTIST III, SAMPLE PREPARATION, ADVANCED TECHNOLOGY

This role is based at our breathtaking site in Eindhoven, The Netherlands and belongs on the Sample Preparation team within Advanced Technology. The immediate team consists of 6 people committed to create, develop, and validate innovative technologies for Cryo-EM and Tomography workflows for our Life Science customers. We are seeking a highly motivated Scientist who is driven by instrumentation development, method/new product development, and keen to bring new products to the market.

REQUIREMENTS AND COMPETENCIES

• Typically requires a Doctorate Degree or equivalent in Physics, Chemistry, Engineering or related scientific subject and 2+ years of industrial experience.
• Demonstrated expertise in complex instrumentation development, most preferably systems including one or more of: charged particle beams, high voltage, high vacuum, precision motion, data acquisition.
• Demonstrated ability to function in a lab-based research environment. Ability to troubleshoot equipment and implement solutions.
• Data analysis skills using Python, C++, C# or similar, and sufficient hand-eye coordination to handle and work with small delicate objects.
• Knowledge in at least one of the areas: electron microscopy, transmission electron microscopy, mass spectrometry, microfluidics, optical detection, cryogenic equipment and concepts, surface chemistry, protein purification,
• Experience with statistical engineering tools and ability to handle large amount of data.
• Strong sense of ownership for work you are doing and responsibilities. Strong communication to diverse audiences, eagerness to learn.
  We offer a stimulating work environment in an international organization with ample prospects to grow and develop a long-term career. The role is at the forefront of high technology with opportunities to interact with customers in academia and pharmaceutical industry.

WHAT WILL YOU DO? AND HOW WILL YOU MAKE AN IMPACT?

You will join an outstanding team of scientists and engineers and will focus on instrumentation development for Cryo-EM sample preparation. Cryo-EM workflow is a multi-step process that involves multiple interconnected hardware and software systems to prepare and qualify samples, recording vast amounts of data and images, and processing the collected data into meaningful information. The focus of this position is on creating experimental test stands allowing proof of principle and proof of concept development. The purpose is to develop new methods for embedding proteins within a thin layer of ice on a TEM grid. These science-intensive investigations will lead to early adopter testing and then to full commercialization. You will work closely with other scientists, architects, project managers within the larger Research & Development organization, as well as business unit, sourcing, operations, and service partners.
Check out these videos to get more insight in what it means to work on our sophisticated High-Tech Electron Microscopes. These high-end tools are being developed, market and manufactured in our cleanrooms. How to make a microscope • Site impression Eindhoven

KEY RESPONSIBILITIES

• Develop hardware instrumentation from a theoretical phase though bench testing and early customer adoption. Define and independently complete research projects supporting sample preparation for cryo electron microscopy.
• Analyze, evaluate, and report on new technologies including publications, patents, and applications. Drive the development of intellectual property including invention disclosures and patent applications.
• Collaborate with colleagues and customers to drive the creation of innovative projects capable of creating new markets and applications. Report results out to multiple levels of business leadership and provide recommendations for further action.