Scientist

at  Legend Biotech EU

COMPANY INFORMATION

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen Biotech, Inc. to develop, manufacture and commercialize ciltacabtagene autoleucel (cilta-cel). Through our strategic partnership, we look to advance the promise of an immunotherapy in the treatment of multiple myeloma.

QUALIFICATION

• Fluent oral communication, reading and writing skill in English
• Cooperation and collaboration spirit
• Trouble shooting and problem solving skill
• Excellent attention to detail and meticulous bench work with a solid understanding of aseptic cell culture techniques (preferably with human primary cells)

EDUCATION:

• At a minimum, a PhD (preferred) or MSc + 2 years of relevant experience in Biology, Immunology, Oncology, Genetics/Microbiology, Biotechnology, Bioengineering, or related fields.

EXPERIENCE:

• Experience of a range of in vitro skills such as in vitro co-cultures, cytotoxicity assays, flow cytometry, molecular biology and PCR.

CAPABILITIES, KNOWLEDGE, AND SKILLS:

• Familiarity with immune and/or tumor cell analytical methods, including cytotoxicity assays, commonly used to characterise cell-therapy-based modalities.
• Prior experience with plate and cell-based assays including techniques such as molecular biology, digital and quantitative PCR desirable.
• Experience with primary immune cell magnetic isolation and culture
• Experienced in independently designing and executing experiments inclusive of data analysis.
• Understanding of statistical analyses and commonly used statistical software (e.g. GraphPad).
• Excellent organization skills: planning and task management including prioritization, creating and keeping deadlines.
• Experience in 3D culture.
• Excellent interpersonal skills and communication skills, both verbal and written.
• A proven ability to be highly productive and successful in a high pace work environment
• Good problem-solving skills and logical approach to solving scientific problems
• Work as part of a multi-disciplinary team with other scientists, engineers and manufacturing personnel.
• Capable of communicating results in concise and clear presentations and reports.

Roles/Responsibilities include, but are not limited to, the following:

• Support and/or lead research activities including design, execution, statistical data analysis and interpretation of scientific experiments.
• Collect and analyse data from various assays used to characterize cell-therapy-based modalities.
• Analyse and translate research results into key conclusions linked to experiment deliverables.
• Prepare presentations and present scientific data at internal meetings.
• Author and review SOPs, study protocols, reports and other scientific and quality documents.
• Critically analyse processes for continual improvements.
• Engage in all required departmental meetings and work closely with cross-functional teams.