Scientist/Senior Scientist – Biological Analytical Development

at  Zoetis

Role Description
Scientist/Senior Scientist – Biological Analytical Development
Zoetis is a global animal health company dedicated to supporting customers and their businesses. Building on 60 years of experience, we deliver quality medicines, biopharmaceuticals and vaccines, complemented by diagnostic products and genetic tests and supported by a range of services. We are working every day to better understand and address the real-world challenges faced by those who raise and care for animals in ways they find truly relevant.
Zoetis discovers, develops, and manufactures a diverse portfolio of animal health medicines, biopharmaceuticals, and vaccines designed to meet the real-world needs of veterinarians and the livestock farmers and companion animal owners they support. Zoetis has the first monoclonal antibody therapy for treating atopic dermatitis in dogs. We are currently seeking to fill new positions to support our growing biopharmaceutical portfolio.
Zoetis Veterinary Medicine Research and Development, Analytical Sciences, in Kalamazoo, MI, is seeking an analytical scientist at the Scientist/ Senior Scientist level. The successful candidate will possess a strong foundation in protein and/or carbohydrate chemistry. The candidate must be highly motivated to contribute to the characterization of, and novel method development for, biological products. Agility in data analytics is highly preferred. Self-motivation, excellent problem-solving skills and communication, and an ability to work independently and within a group are essential to this role.

Responsibilities include, but are not limited to, the following:

• Characterization of biological molecules, identify degradation pathways, and define critical quality attributes. Contribute to analytical method development (including streamlining automation for samples preparation), qualification, validation and transfer activities. Primary techniques are HPLC, mass spectrometry, electrophoresis, spectrophotometric, and microplate assays.
• Maintain familiarity with scientific literature and apply new knowledge appropriately to projects.
• Convey complex and nuanced concepts to interdisciplinary teams through oral and written presentations, and reports.
• Work in collaboration with other scientists to advance the development of state-of-the-art techniques to characterize biopharmaceutical products, assays, and tools. Develop high-throughput and/or automated methodologies for sample preparation.
• Develop creative solutions to moderately complex problems.
• Document and communicate results in laboratory notebooks, technical reports, and oral presentations.

Minimum Qualifications:

• PhD in Chemistry, Biochemistry, Computational Biology, or other related discipline, with at least 1-3 years of industry experience, preferably in the biopharmaceutical industry. BS or MS with extensive industry experience.
• Motivated self-starter with excellent communication (oral and written), interpersonal, and organizational skills.
• Extensive experience in separation technologies including multiple modes for HPLC and capillary electrophoresis (e.g., SEC, RP-HPLC, IEX, icIEF, CE-SDS) for the analysis of complex proteins
• Experience in developing, and validating biopharmaceutical analytical methods, including liquid chromatography (UHPLC and nano LC), electrophoretic separations, glycoprotein analysis, and mass spectrometry.
• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
• Solid understanding of protein structure, post-translational modifications (including glycans) and potential sequence liabilities (e.g oxidation, deamidation, and clipping)
• Prepare comprehensive analytical reports and presentations, conveying findings to both technical and non-technical stakeholders.
• Strong problem-solving skills and a proactive attitude toward process improvement

Preferred Qualifications:

• Proficiency in data analytics tools such as JMP, Tableau, and Minitab, with the ability to manipulate, analyze, and visualize complex data sets.
• Familiarity with peptide mapping by LC-MS/MS (UHPLC and nanoLC), intact mass analysis, MS/MS for protein and carbohydrate structural elucidation.
• Ability to recognize anomalous and inconsistent results and interpret outcomes.
• Familiarity with biopharmaceutical manufacturing processes, including cell culture, purification, and formulation.
• Skills and experience in experimental design, technical problem solving and continuous improvement; deepens technical knowledge through exposure and continuous learning
• Knowledge of regulatory guidelines such as ICH, USP, EMA or FDA.

Full time
Regular
Colleague
Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.
Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of “@zoetis.com”. In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis

• Characterization of biological molecules, identify degradation pathways, and define critical quality attributes. Contribute to analytical method development (including streamlining automation for samples preparation), qualification, validation and transfer activities. Primary techniques are HPLC, mass spectrometry, electrophoresis, spectrophotometric, and microplate assays.
• Maintain familiarity with scientific literature and apply new knowledge appropriately to projects.
• Convey complex and nuanced concepts to interdisciplinary teams through oral and written presentations, and reports.
• Work in collaboration with other scientists to advance the development of state-of-the-art techniques to characterize biopharmaceutical products, assays, and tools. Develop high-throughput and/or automated methodologies for sample preparation.
• Develop creative solutions to moderately complex problems.
• Document and communicate results in laboratory notebooks, technical reports, and oral presentations