Scientist / Senior Scientist, Cell Type Development (Products Support)

at  Bit Bio

bit.bio is an award-winning spinout from the University of Cambridge. Our breakthrough technology combines synthetic and stem cell biology for the precise, efficient and consistent reprogramming of human cells used in research, drug discovery, and cell therapy. At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future. To do this we need talented and curious people who want to make an impact on the future of science and therapeutics.
As a team of individuals, we value science, collaboration, openness, curiosity and creativity. We are united by trust and respect for each other.

WITH ESSENTIAL EXPERIENCE IN…

• Strong practical and theoretical background in hESC or hIPSC culture and differentiation/reprogramming OR Functional cell type experience.
• Strong practical and theoretical background in characterisation of cells in vitro.
• Well-rounded practical experience and knowledge of cellular assays and cellular phenotyping (e.g. immunocytochemistry, MEA).
• Well-rounded practical experience in molecular assays, molecular biology, and their downstream analysis (qRT-PCR, bulk and single cell RNA sequencing).
• Are a solution-oriented problem solver.
• Ability to manage and prioritise own workload
• The ability to work collaboratively between teams and specific platforms.

YOUR ROLE IN OUR TEAM:

Reporting to the Principal Scientist, Cell Type Development, you will be instrumental in providing technical support and expertise across a range of specialised techniques critical to our operations and product excellence. Products Support is uniquely positioned to address the growing demands of our customers, particularly in the areas of adapting culturing SOPs for mid/high throughput approaches suitable for high-content imaging, functional assays (MEA), and FACS sorting (amongst others) and analysis.
Our objective is to work closely with the Products team within Commercial to provide comprehensive and responsive support, ensuring that our clients have the tools and expertise they need to maximise the value of our products.

YOUR KEY RESPONSIBILITIES WILL INCLUDE:

• Develop, and execute experimental assays on specific cell types of interest from human pluripotent stem cells using cellular reprogramming approaches.
• Analyse and interpret data from cellular reprogramming experiments, report data, and perform experimental troubleshooting when required.
• To work in collaboration with R&D departments and the imaging and flow teams to co-develop cell- specific cell characterisation assays.
• Become the in-house expert on multiple cell types, offering tailored support and developing specialised knowledge to enhance our product offerings.
• Provide advanced technical assistance for specialised techniques including high-content and live imaging, microelectrode array (MEA) functional assays, and fluorescence-activated cell sorting (FACS).
• Optimise and adapt culturing standard operating procedures (SOPs) to enable mid to high-throughput methodologies that complement our high-content imaging and analysis capabilities.
• Collaborate closely with the commercial Products team to deliver responsive, comprehensive support to our customers, ensuring they fully benefit from our cell type products.
• Innovate and contribute to the continuous improvement of our support strategies, addressing the evolving demands of our customer base and staying ahead of industry trends.
• Actively lead in developing and maintaining the core cultural aspects of the company.