Senior Associate Scientist, MSAT LM DS

at  Johnson Johnson

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
Are you an experienced scientist with a background in Large Molecules who enjoys translating scientific knowledge into business applications? Do you thrive in collaborative environments and find motivation in improving patients’ lives? If so, we would love to hear from you! Johnson & Johnson is currently seeking a Senior Associate Scientist to join our Manufacturing Science and Technology (MSAT) Lab located in Leiden, the Netherlands. The MSAT Lab operates within the Large Molecule Drug Substance (LM DS) platform, which is a segment of the global MSAT organization.
As we work to enhance MSAT capabilities to fully own our current and future commercial products, we are establishing a dedicated laboratory specializing in Large Molecules (mAbs, complex glycoproteins, bi- & tri-specifics). This lab will house small-scale equipment including 2-10 L bioreactors (fed-batch and continuous perfusion), downstream processing and process analytical lab equipment. The MSAT Lab will support Life Cycle Management of commercial products and Secondary Technology Transfers. Our lab will conduct satellite runs in Leiden and for EU & Row address complex investigations, process improvements, and serve as a non-routine sample hub. Currently, we are focused on onboarding scientific knowledge and ensuring the operational readiness of the MSAT LM DS lab by developing a roadmap for data management and enabling digital connectivity.
To strengthen our team, we are looking for a Senior Associate Scientist to take on two key responsibilities:
1. Lead the construction of the digital roadmap for the MSAT LM DS Lab.
2. Serve as a hands-on scientist to strengthen the scientific rigor of the team, particularly in taking over R&D responsibilities for LCM portfolio and secondary tech transfers that are transitioning to MSAT.
If you are passionate about combining science with business applications and improving patient outcomes, we invite you to apply!

Key Responsibilities:

• Lead the construction of the digital roadmap for the MSAT LM DS Lab:
• Alignment with JJT and local execution system teams on data pipeline architecture
• Scouting and selection of fit-for-purpose electronic lab notebook
• Scouting and selection of fit-for-purpose sample management system including bar-coding capability
• Design and mapping of lab equipment data connectivity to PI data historian, where applicable
• Design and mapping of key lab equipment connectivity to a central automation system for (remote) control, where applicable
• Scouting and selection of data visualization and analytics tools relevant for MSAT LM DS lab (e.g., Tableau dashboards, DataHow/Microsoft Fabrics, Minitab/JMP, SIMCA, SynTQ, Python/R)
• Creation of implementation plan and budget forecast estimation for technology deployment

As a scientist, your key responsibilities include:

• Independently lead complex investigations to improve the robustness and reliability of commercial manufacturing processes for large molecules, including the design of experiments (DoE) and conducting lab studies.
• Serve as the process owner and scientific expert, supporting commercial product teams and secondary technology transfer projects by providing technical leadership and managing relationships with both internal and external stakeholders.
• Collaborate with global partners to identify and implement process improvements and innovations.
• Develop and maintain comprehensive technical documentation to support continuous improvement initiatives and knowledge sharing.

QUALIFICATIONS

Educational Background:

• 2+ years with advanced degree MSc / MBA / EngD / PhD or equivalent OR 5+ years proven experience with bachelor’s degree or equivalent in Biochemistry, Biotechnology, Chemical Engineering, or a related field.

Experience:

• 2+ years in a relevant industry setting, preferably in biopharmaceuticals or biotechnology, focusing on large molecule manufacturing processes.

Technical Skills:

• Strong expertise in biologics manufacturing processes, including upstream and downstream processing.
• Experience with design of experiments (DoE) and statistical analysis tools.
• Familiarity with process analytical technologies and quality by design (QbD) principles.

Communication and Leadership:

• Excellent communication skills for engaging with cross-functional teams and stakeholders.
• Proven ability to lead projects and investigations independently.

Project Management:

• Proficient project management skills to handle multiple projects and priorities simultaneously.

Problem-Solving Abilities:

• Demonstrated ability to troubleshoot complex scientific issues and develop innovative solutions.

Regulatory Knowledge:

• Understanding of regulatory requirements and industry standards, including GMP (Good Manufacturing Practice) compliance.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong

Key Responsibilities:

• Lead the construction of the digital roadmap for the MSAT LM DS Lab:
• Alignment with JJT and local execution system teams on data pipeline architecture
• Scouting and selection of fit-for-purpose electronic lab notebook
• Scouting and selection of fit-for-purpose sample management system including bar-coding capability
• Design and mapping of lab equipment data connectivity to PI data historian, where applicable
• Design and mapping of key lab equipment connectivity to a central automation system for (remote) control, where applicable
• Scouting and selection of data visualization and analytics tools relevant for MSAT LM DS lab (e.g., Tableau dashboards, DataHow/Microsoft Fabrics, Minitab/JMP, SIMCA, SynTQ, Python/R)
• Creation of implementation plan and budget forecast estimation for technology deploymen

As a scientist, your key responsibilities include:

• Independently lead complex investigations to improve the robustness and reliability of commercial manufacturing processes for large molecules, including the design of experiments (DoE) and conducting lab studies.
• Serve as the process owner and scientific expert, supporting commercial product teams and secondary technology transfer projects by providing technical leadership and managing relationships with both internal and external stakeholders.
• Collaborate with global partners to identify and implement process improvements and innovations.
• Develop and maintain comprehensive technical documentation to support continuous improvement initiatives and knowledge sharing