Senior Research Fellow- CRUK Glioma CoE Transition

at  University College London

ABOUT US

Cancer Research UK (CRUK) have awarded funding to renew the UCL-Edinburgh CRUK Glioma Brain Tumour Centre of Excellence (CoE). The CoE features an ambitious research programme to develop a deeper understanding of the fundamental biology of glioma and harness this knowledge to drive new translational approaches to improve patient outcomes. The CoE’s core themes are:

• Pre-disease biology: understand how glioma is initiated from neural stem and progenitor cells.
• Tumour promotion: delineate how incipient glioma clones interact with the microenvironment, with a focus on injury programmes and neuroinflammation as key drivers of progression.
• Therapy resistance: define the nature of persister cells that survive immediately after treatment to identify targetable vulnerabilities.
• Therapeutic intervention: deploy multidisciplinary identify and prioritise new treatment strategies emerging from the Centre’s scientific discoveries

The CoE brings together researchers from University College London and The University of Edinburgh to advance UK brain tumour research. Key pillars of the CoE are dissemination of state-of-the-art preclinical models to accelerate scientific discover, deployment of multidisciplinary approaches to explore new scientific froniters and therapeutic intervention, capacity building and training of the next generation of glioma reaserchers in the UK. In its second quinquennium, this interdisciplinary and collaborative network will support ground-breaking research, the development innovative therapies, diagnostics and stratification strategies in addition to providing a clinical and translational pipeline for discovery science in glioma. The London partners will also work closely with University College London Hospitals and Queen Square.
The post is funded for 3 years in the first instance.

We are seeking transition fellows with a strong publication track record to join the CRUK Glioma CoE. The successful candidates will will develop an independent programme of research, relevant to the themes of the CoE. Fellows will be expected to apply for independent research funding supported by existing research programmes on brain tumours. They will receive a generous consumables budget and priority access to CoE infrastructure, including preclinical models, and will be supported by a variety of mentoring schemes.