Senior Scientist I/ II, Biophysics

at  Pharmaron

Job Introduction
At Pharmaron, we are seeking a Senior Scientist for our Biophysics team to drive innovative drug discovery projects through the application of advanced biophysical techniques. This role offers the opportunity to significantly impact scientific research in a collaborative and cutting-edge environment, furthering both your professional and technical expertise.

REQUIREMENTS:

• Ph.D. in Biochemistry, Biophysics or a related field, or an M.S. with at least three years of relevant work experience, or a B.S. with five years of relevant work experience
• Experience using biophysical techniques used to analyse protein-protein interactions and protein-small molecule interactions.
• Practical experience with biophysical techniques such Microscale Thermophoresis (MST), Isothermal Titration Calorimetry (ITC), Differential Scanning Fluorimetry (DSF) is required.
• Candidates with experience running FP, FRET, kinetic FRET assays or Mass Spectroscopy with relevant knowledge in Drug Discovery field will also be considered
• Expertise with the kinetic and thermodynamic characterization of ligand binding as well as quantitative data management and analysis
• Excellent communication skills and ability to present rationale, key data, issues and accomplishments to other members of the scientific team
• Good fit with Pharmaron culture and values of highly collaborative, team-oriented research

To support biology projects by working independently to plan, execute and deliver on project goals.

• Demonstrate competency in the core laboratory skills required to support biology assay development, validation and screening. Such skills include, but are not limited to, routine use of core instrumentation and laboratory techniques, guided use of higher end laboratory techniques and instrumentation, and an understanding how their work influences drug discovery.
• Execute experiments, interpret results, and be able to plan and recommend next steps and/or additional experiments in a timely manner to solve scientific issues. Where appropriate the individual will seek guidance (from a scientific supervisor / Line Manager) due to the level of complexity and/or the requirement for strategic input.
• Communicate with cross-functional teams to ensure that scientific work is appropriately reported via laboratory notebooks and presentations both internally and externally to the client.
• Document and report results of all experiments in a manner consistent with department practices and governing procedures, as applicable.
• Document and report results of all experiments in a manner consistent with department practices and governing policies.

Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.
We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.
Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams.
In addition, a Formulation Development team was also recently established.

The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).

• We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
• We offer state of the art working environment on site.
• We offer the opportunity for growth and development and will support funding for relevant training and development programmes.