Senior Scientist - Med Chem

at  Charles River Laboratories

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

JOB SUMMARY

Are you a MSc/PhD graduate within a chemistry discipline?
Have you got the desire to join a company who play a part in improving health and lives?

DO YOU HAVE A PASSION FOR DRUG DEVELOPMENT?

Charles River are looking for a Senior Scientist - Medicinal Chemistry to be based at our client site in Hatfield on an initial 12 month FTC. In this role, you will be working as part of a team of enthusiastic medicinal chemists designing and synthesising novel compounds with the goal being to identify a potential candidate suitable for drug development.

PROFILE AND REQUIREMENTS

• MSc/PhD in a relevant discipline (Synthetic Chemistry/Medicinal Chemistry/Organic Chemistry)
• Previous exprience of working in a similar role within the CRO/Biotech/Pharma industry
• Practical and theoretical knowledge of synthetic organic chemistry to enable efficient planning, execution and problem-solving of synthetic routes towards assigned target compounds, as well as routine purification and analysis of intermediates and final compounds.
• To have good attention to detail, organisational and time management skills.
• To have a dynamic, can-do attitude and a flexible approach to problem solving.
• A desire to develop a career discovering new medicines for the future.
• A commitment to personal development to enable future career progression.
• A passion for practical synthetic chemistry.
• Identify synthetic chemistry problems and work with colleagues to implement solutions.
• To be able to interpret NMR and mass spectrometry data.
• To be able to use scientific literature and provide solutions to technical problems.

• Plan and execute efficient synthetic routes to deliver final compounds to benefit your assigned project.
• Solve problems with synthetic routes and individual reactions or purifications to access target compounds aligned with project priorities.
• Follow local legislation and policies and procedures on safety and quality. Act with due care for the safety of yourself and others at all times.
• Present results, issues and plans around your own work at regular internal or external meetings for your project and client. Clearly communicate status of your own work, issues encountered and proposed solutions with your chemistry or project leader.
• Proficient in practical use of standard chemistry lab equipment to efficiently and safely complete reactions.
• Analyse reactions and isolated materials by LC/MS, NMR and other techniques as required to demonstrate structural identity and purity of intermediates and final compounds.
• Collaborate with chemistry colleagues to maintain a tidy and safe lab environment