Senior Scientist, Neuroscience Discovery

at  Johnson Johnson

Johnson & Johnson (J&J) is recruiting for a Senior Scientist to join our Neuroscience Discovery group based in Springhouse, PA, USA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
You will be applying cutting-edge science, exploring new techniques, and developing innovative platforms e.g., complex IPSC cellular models of disease and high content imaging, to identify novel targets and validate them sufficiently to enter the Neuroscience Discovery Portfolio. You will work closely with our Data Science colleagues to leverage large data sets e.g. proteomics and transcriptomics, as well as genetic and real-world evidence data to shape the discovery portfolio. Your work will be instrumental for us to continue building a transformational Neuroscience portfolio to develop novel treatments for Neurodegenerative and Neuropsychiatric Diseases. This will require excellent communication and teamwork skills, an appetite for innovation, and a keen attention to detail and organization. You should have a considerable sense of purpose and drive, be mindful of the considerable unmet medical need and imperative to generate impactful therapeutics in Neuroscience and embody the critical importance of translation of insights from biology and data science to the vision and mission of Johnson & Johnson.

Your Key Responsibilities:

• Developing complex human cell models of neuropsychiatric and neurodegenerative disorders to identifying and validating novel druggable targets for the treatment of Neuropsychiatric and Neurodegenerative diseases that are aligned with our Disease Area Strategy.
• Collaborating closely within the Global Biology function and with other functions, including but not limited to, Data Sciences, Discovery Technology & Molecular Pharmacology and In Silico Discovery to integrate data from human cell models, human omics data, and other datasets coupled to AI and machine learning.
• Effective oral and written communication to ensure alignment across functions and within the neuroscience department.

QUALIFICATIONS

Required:

• A PhD degree in Neuroscience or related biological research discipline (such as cellular biology or biochemistry), or a BSc with at least 8 years pharmaceutical experience
• Strong knowledge in cell and molecular biology, and iPSC modeling.
• Demonstrated experience working with human cell models to develop a platform to explore disease pathways and validate novel targets.
• Strong skills in biochemical assays and cell imaging.
• Ability to independently conduct and interpret complex biological experiments, self-motivated to learn and develop new techniques, keep accurate records, and comply with company policies.
• Ability to work in teams and develop and maintain strong internal network.
• A proven track record of evaluation of novel cell mechanisms in Neuroscience or related biological field, that is reflected in publications in peer reviewed journals.
• Proactively creates a purpose driven environment by aligning Johnson & Johnson’s Credo and Leadership Imperatives with the strategies and goals of the team and enterprise.
• Broadens external scientific visibility and reputation of J&J by publications and participating in scientific seminars and discussion forums.
• Crafts presentations of research outcomes and progress to senior leaders by owning the analysis of results and providing critical feedback.

Preferred:

• Experience in running high-thruput assays and analysis of large data sets.
• Experience working in drug discovery environment.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against based on disability

• Developing complex human cell models of neuropsychiatric and neurodegenerative disorders to identifying and validating novel druggable targets for the treatment of Neuropsychiatric and Neurodegenerative diseases that are aligned with our Disease Area Strategy.
• Collaborating closely within the Global Biology function and with other functions, including but not limited to, Data Sciences, Discovery Technology & Molecular Pharmacology and In Silico Discovery to integrate data from human cell models, human omics data, and other datasets coupled to AI and machine learning.
• Effective oral and written communication to ensure alignment across functions and within the neuroscience department