Study Director I - Pharma Oncology

at  Charles River Laboratories

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

JOB SUMMARY

We are seeking a skilled, passionate and energetic Pharmacology Study Director to provide scientific leadership for all technical aspects of studies. The qualified candidate will work closely with our clients and our established teams in the design, conduct, analysis, interpretation and reporting of a wide variety of Oncology studies in a fast paced and dynamic environment. Responsibilities of this position include extensive interaction and communication with client scientists in the discovery oncology research area of study management, interpretation and reporting.

JOB QUALIFICATIONS

Education: Bachelor’s degree (B.S./B.A.) or equivalent in a scientific related discipline. Related Master’s degree (M.S./M.A.) or PhD/DVM preferred.
Experience: Minimum of 6 years related experience in the contract research, academic or pharmaceutical industry required.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

• Expertise in in-vivo animal skills necessary to support xenograft oncology studies.
• Ability to set-up and validate in vivo cancer models (xenograft rodent models)
• Evaluate anticancer NCEs for pharmacokinetic/pharmacodynamics/efficacy in xenograft models
• Conduct and oversee in vivo studies for efficacy and target inhibition (tumor implantation/inoculation, compound dosing, tumor excision/biopsy).
• Generate high-quality protocols, amendments, and reports appropriate for assigned studies.
• Review, interpret, integrate, and present data on assigned studies, using the assistance of senior scientific staff as appropriate.