162124 Associate Professor of Neuroscience (Fixed-Term, 3 Years)

at  Kbenhavns Universitet

JOB DESCRIPTION

Immunotherapies based on antibodies that scavenge amyloid-beta are, so far, the only viable options for the treatment of Alzheimer’s disease (AD). However, the transport mechanisms across the blood-brain barrier (BBB) and pharmacokinetics (PK) of therapeutic antibodies are incompletely understood. Consequently, their brain uptake is predictably limited, and the dosage increase required to mitigate low brain uptake results in off-site effects in patients in the periphery and the central nervous system. The scientist taking this position will provide crucial novel insights to PK and BBB transport of therapeutic antibodies used for the treatment of AD and provide results that can be used to optimize the engineering of therapeutic compounds to effectively treat AD.

The associate professor’s responsibilities will primarily consist of:

• Research, including publication/academic dissemination
• Research-based teaching, including associated examination
• Research leadership, including guidance and supervision of researchers
• Obligation to share knowledge with the rest of society, including participation in public debate
• Academic assessments

REQUIRED QUALIFICATIONS

Six overall criteria apply for associate professor appointments at the University of Copenhagen. The six criteria (research, teaching, societal impact, organisational contribution, external funding and leadership) are considered a framework for the overall assessment of candidates. Find information about each criterion here: https://employment.ku.dk/faculty/criteria-for-recognising-merit.

Specific qualifications for position:

• PhD or equivalent degree in natural or medical science
• Advanced skills and experience in 2-photon microscopy imaging in live mice
• Prior published work on drug delivery, brain transport mechanisms and vascular function
• Relevant professional experience in ImageJ and computational image analysis
• High technical skills in real time data acquisition and instrumentation control
• Enthusiasm, motivation, flexibility. and confidence.

Furthermore, each applicant must be able to document:

• Research qualifications at the level that can be achieved by satisfactorily completing a period of employment as an assistant professor/postdoc, but may also be obtained in other ways
• Teaching qualifications and pedagogical competencies
• Research-based teaching

The associate professor is also required to possess good interpersonal and communicative skills.

• Research, including publication/academic dissemination
• Research-based teaching, including associated examination
• Research leadership, including guidance and supervision of researchers
• Obligation to share knowledge with the rest of society, including participation in public debate
• Academic assessment