Associate Scientist - Cell Therapy Preclinical Biology

at  BristolMyers Squibb

WORKING WITH US

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
The Cell Therapy Preclinical Biology team in the Cancer Immunology and Cell Therapy Thematic Research Center has an opening for a highly motivated and creative Associate Scientist with a dedication to discovery and development of novel engineered CAR T and eTCR T cell therapeutics for the treatment of cancer. The successful candidate will have experience setting up in vitro functional assays to measure T cell function, including: proliferation, cytokine production, phenotypic analysis and cytotoxic activity. Flow cytometry experience is essential; experience with high throughput methods and/or gene editing is a plus. This position will involve interfacing with senior researchers to execute studies, analyze data and communicate results. This position is ideal for the innovative scientist who is driven and passionate about cell therapy in a fast-paced, collaborative environment.

In the role as an Associate Scientist within the Cell Therapy Preclinical Biology group, the ideal candidate:

• Applies scientific and / or technical skills and functional knowledge to execute experiments within own group / project team
• Analyzes and interprets experimental data
• Works predominantly within established procedures, sometimes in loosely defined problem-solving situations
• Begins to participate in troubleshooting of routine problems and initiatives related to continuous improvement or development of new approaches / technologies
• Organizes and presents data / information for internal and external audiences
• Maintains electronic notebooks with detailed documentation of protocols, study designs and results
• Generates, expands, characterizes, and cryopreserves CAR T cell and eTCR T cells
• Phenotypically and functionally analyzes CAR and eTCR T cells using flow cytometry and IncuCyte
• Evaluates CAR and eTCR function uses in vitro co-culture assays with cancer cell lines

Basic Qualifications:

• Bachelor’s Degree in biological science, immunology, bioengineering, or related discipline
• 2+ years of academic and / or industry experience

Preferred Qualifications:

• Requires developed knowledge of the principles and concepts of biological sciences, immunology, bioengineering, or related discipline
• Experience with in vitro technologies typically employed to assess T cell functionality including but not limited to MSD, IncuCyte-based assays, multi-parameter flow cytometry for phenotypic characterization of T cells, T cell activation assays, T cell proliferation analysis.
• Experience with high throughput, automation, gene editing, and/or imaging technologies desired but not required.
• Able to recognize potential problems and recommend/develop appropriate solutions
• Ability to work productively as both team member and as individual contributor
• Strong communication skills for working with cross-functional teams as well as cross-departmental colleagues
• Requires strong organizational skills to ensure thorough and timely documentation of experiments
• Strong quantitative and analytical skills are desirable

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

• Applies scientific and / or technical skills and functional knowledge to execute experiments within own group / project team
• Analyzes and interprets experimental data
• Works predominantly within established procedures, sometimes in loosely defined problem-solving situations
• Begins to participate in troubleshooting of routine problems and initiatives related to continuous improvement or development of new approaches / technologies
• Organizes and presents data / information for internal and external audiences
• Maintains electronic notebooks with detailed documentation of protocols, study designs and results
• Generates, expands, characterizes, and cryopreserves CAR T cell and eTCR T cells
• Phenotypically and functionally analyzes CAR and eTCR T cells using flow cytometry and IncuCyte
• Evaluates CAR and eTCR function uses in vitro co-culture assays with cancer cell line