Associate Scientist – Critical Reagent Management Team (non-PHD)

at  Pfizer

Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
The Protein and Bioanalytical Sciences (PBS) team is focused on creating and delivering novel research test articles for preclinical evaluation. As an Associate Scientist, you will be at the center of our operations, and you’ll find that everything we do is in line with an unwavering commitment to quality. This position is responsible for managing critical reagent inventories, preparing and delivering various research compounds (such as Antibody Drug Conjugations (ADCs) and toxic linker payloads), overseeing the care and maintenance of HPLCs and other analytical instruments, and periodically performing antibody conjugations. This person will play a critical role in supporting our team and in communicating reagent availability to our scientists throughout Pfizer Oncology Research. Your strong foundation in quality scientific practices will help the team in meeting critical deadlines and exceeding milestones. You will be relied on as a technical contributor to make decisions that involve direct application of your knowledge. It is your hard work and focus that will make Pfizer ready to achieve new breakthroughs and help patients across the globe.

How You Will Achieve It

• Preparation of critical reagents and formulations.
• Regular care and maintenance of equipment, including HPLC, LC/MS, FPLC, and spectroscopy instrumentation.
• Troubleshooting and repairing of HPLC, LC/MS, and FPLC systems.
• Regular maintenance and auditing of robust inventories.
• Precise aliquoting and delivery of ADC doses.
• Timely recording of experimental details in ELN (electronic lab notebook).
• Ordering/receiving new reagents and equipment for general laboratory use.
• Managing large reagent inventories with Freezerworks software.
• Performing regular audits of multiple reagent inventories.
• Routinely generating reports and reviewing reports with manager, project leads and other research associates.
• Evaluating new lab efficiencies.
• Regular collaboration with team members and strong communication skills.
• Routine laboratory cleaning.
• Occasionally performing antibody reductions and conjugations.
• Routinely analyzing ADC properties using analytical instruments (such as HPLC and MS) or assays (such as free drug, endotoxin, DC assay, etc).

Qualifications

Must-Have

• Bachelor’s degree in biochemistry, chemistry, or related field with 0-2 years relevant experience, or equivalent.
• Highly detail-oriented with strong analytical, organizational, and multi-tasking skills.
• Ability to perform routine tasks independently and commitment to high quality analysis and documentation.
• Willingness to work with potent cytotoxic compounds and following safety protocols.
• Laboratory experience in a relevant field of science.
• Good computer skills including word processing, Excel, PowerPoint, and relevant scientific software.

Nice-to-Have

• Hands-on laboratory experience (excluding college coursework).
• Protein and/or antibody handling experience.
• Previous experience with antibody or protein conjugations.
• Practical knowledge of analytical HPLC chromatography of proteins and UV spectroscopy.
• Hands-on experience of HPLC system maintenance and repairing is preferred.
• Experience working with protein liquid chromatography or spectroscopy instrumentation.
• Knowledge of protein stability and formulation.
• Prior experience working with electronic lab notebooks and/or LIMS systems.

Additional Information:

• Work Location- On Premise

The annual base salary for this position ranges from $54,700.00 to $91,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development

Please refer the Job description for details