Executive Director, Global Program Team Lead

at  Alexion PharmaceuticalsInc

Location: Boston, United States
Job reference: R-172490
Date posted: 04/04/2024
The Executive Director, GPTL is responsible for providing strategic direction and leading the global drug development for one or multiple Global Program Teams with complex Phase III clinical development programs. Typically, a GPT Lead would conduct their GPT work as part of a GMT and under the supervision of a GMT Lead (except for medicines with only one indication).
As the accountable program(s) owner/CEO, the Global Program Team Leader (GPTL), leads and chairs the Global Program Team (GPT), leading the creation of an integrated development plan, maintaining a strategic focus and ensuring the GPT’s commitments are met.
The GPTLs role is one of leadership, being proactive and interactive, and emphasizing partnership with all GPT members and other stakeholders and consultants both within and outside R&D. The GPTL should stimulate creative and productive discussion, motivate, ownership and urgency (when necessary) as well as robust discussions of risk identification and mitigation opportunities, and ensure clarity of purpose and responsibilities with the GPT. The GPTL has negotiation and persuasion skills necessary to ensure success of the program and sets goals for the GPT and specific program-related goals for the Core Team members. GPTLs are the “voice” of the GPT up the line (GMT Leadership, R&D and VISion Leadership, Development and Commercial Steering Committee and Executive Committee), and the principal liaison and partner to other groups.
In stand-alone programs for a medicine with only one indication (i.e., no GMT), the GPT is co-led by the R&D GPTL and a Commercial (VISion) Team GPTL.

• Program ownership with final accountability for clear definitions of program goals, plans, decisions and deliverables to meet those goals
• Provides strategic direction and leadership of global development programs from Post-PoC to BLA/NDA/MAA for assigned projects in accordance with the global R&D strategy. Provides global development strategy and leadership for assigned projects to ensure clear goal setting and robust development plans for effective and efficient development. (This will entail working closely with core team members, functional leads, and other colleagues to collaborate and ensure their buy-in and knowledge-sharing in establishing and implement the global development strategy for assigned projects.)
• Ensures that the GPT implements its plans and adheres to key development milestones for assigned projects.
• Accountable for aspects of pre-clinical, CMC, clinical plans and programs across from Post-PoC through commercial approval for assigned projects.
• Leads the global project team and reviews development plans for assigned projects and thorough product lifecycle management for assigned projects.
• Contributes to objective setting and appraisal of core team members for program related activities
• Keeps senior management informed
• Is accountable for the program budget
• Ensures high performance team effectiveness