PhD position: improving infant health through breast milk proteins & peptides

at  Wageningen University Research

WE ARE LOOKING FOR A PHD CANDIDATE WITH AN INTEREST IN ANALYTICAL BIOCHEMISTRY AND BIOINFORMATICS FOR A PROJECT ON BREAST MILK PROTEIN AND PEPTIDE COMPOSITION AND ITS RELATION TO INFANT HEALTH.

Breastfeeding is known to be important for healthy development of infants. One of the many benefits of breastfeeding is the protection against airway infections. Within this project, we will study the role of breast milk composition in the prevention of airway infections in infants, based on evidence that specific factors (proteins and peptides) in human milk may play a role in the protective function of human milk. We will characterize breast milk proteins and peptides, and will determine the link between their presence in breastmilk and airway infections in infants.
Within this PhD project, the aim will be to study the variability in the proteins and peptides in breast milk. We have developed improved methodology for both protein and peptide screening in human milk. However, further improvements still need to be made for the identification of specific peptides. It is expected that the PhD student contributes to this development by working on improved biochemical methods and data analysis. Next, the relation between these breast milk components and infant airway infections needs to be established in collaboration with the PRIMA cohort (Dutch website: https://prima.hetwkz.nl/). In collaboration with another PhD student at the UMC Utrecht, the immunological functionality will be studied of key proteins, including the impact of heating on this functionality.

YOU WILL WORK HERE

This research will be executed within the chair Food Quality and Design. Your supervisors will be Prof. dr. Kasper Hettinga (Food Quality and Design) and Dr. Tim Lambers (FrieslandCampina).
Read the 5 reasons why your future colleagues enjoy working at WUR and watch this video to get an idea of our green campus!

We will recruit for the vacancy ourselves, so no employment agencies please. However, sharing in your network is appreciated. For this position we are looking for a PhD candidate who has the following qualifications:

• a successfully completed MSc degree in biological science, e.g. food, nutrition, biochemistry;
• experience in biochemical analyses, e.g. protein and/or peptide analysis;
• knowledge of and/or experience with complex data analysis;
• strong scientific writing skills (evident from your thesis and/or publications);
• affinity with working in a multidisciplinary group;
• excellent command of written and spoken English.

For more information about this position, please contact please contact Kasper Hettinga by email: kasper.hettinga@wur.nl.
For more information about the procedure, please contact Rutger Voorrips, corporate recruiter by e-mail: rutger.voorrips@wur.nl.

You will work at the Food Quality & Design group, with several external partners (including universities and industries). Within this project, your main tasks will include:

• perform and improve proteomics and peptidomics analyses;
• use bioinformatics tool to analyse the obtained -omics data;
• publishing scientific papers and write a PhD thesis;
• working within a consortium with different scientific researchers as well as companies.

Wageningen University & Research offers excellent terms of employment. A few highlights from our Collective Labour Agreement include:

• partially paid parental leave;
• working hours that can be discussed and arranged so that they allow for the best possible work-life balance;
• the option to accrue additional compensation / holiday hours by working more, up to 40 hours per week;
• there is a strong focus on vitality and you can make use of the sports facilities available on campus for a small fee;
• a fixed December bonus of 8.3%;
• excellent pension scheme.

In addition to these first-rate employee benefits, you will receive a fully funded PhD position and you will be offered a course program tailored to your needs and the research team.
The gross salary for the first year is € 2.770 - per month rising to € 3.539,- in the fourth year in according to the Collective Labour Agreements for Dutch Universities (CAO-NU) (scale P). This is based on a full-time working week of 38 hours. We offer a temporary contract for 18 months which will be extended for the duration of the project if you perform well.
There are plenty of options for personal initiative in a learning environment, and we provide excellent training opportunities. We are offering a unique position in an international environment with a pleasant and open working atmosphere.
You are going to work at the greenest and most innovative campus in Holland, and at a university that has been chosen as the “Best University” in the Netherlands for the 19th consecutive time.