Post Doctoral Fellow in Biochemistry/Oncology

at  University of Alberta

Department Faculty of Medicine & Dentistry - Biochemistry Dept
Posted date February 5, 2024
Closing date Will remain open until filled.
Position Type Full Time

DESCRIPTION

This position offers a benefits package found at Postdoctoral Fellows Benefits.
Location - Work primarily takes place at North Campus Edmonton

POSITION

The Goping lab has a position available for a postdoctoral fellow for one year with the possiblity of extension. We are looking for person with the skills, enthusiasm, and commitment to conduct rigorous scientific studies in the area of breast cancer research. The candidate will play a key role in a multidisciplinary team project that involves generation and molecular characterization of breast cancer Patient Derived Organoids (PDOs). PDOs are generated from an individual patient tumor and are cultured as 3D organoids. The candidate will use PDO culture models to evaluate Patient/PDO drug sensitivity and use next-generation-sequencing to identify mechanisms of resistance. These studies will provide valuable insight on PDO potential as precision health tools. The position provides opportunities for self-directed learning and possible leadership roles within an exciting and supportive multidisciplinary research team.
We are looking for a person who is a motivated self-starter and a team player. This individual enjoys challenges. They are both independent and collaborative. The successful candidate will be responsible for PDO generation and extensive molecular/cellular characterization

MINIMUM QUALIFICATIONS

• PhD degree in Biochemistry, Cell Biology, or related discipline
• Extensive expertise in cell biology methods (cell culture and related analytical methods, microscopy)
• Expertise in biochemistry methods (molecular biology, protein analysis)
• Expertise in data analysis and statistics
• Excellent organizational and communication skills
• Strong independent research skills and also thrives in a collaborative environment
• Motivated to learn and help drive breast cancer research projects with translational potential
• Committed to bringing strength to the team
• Self-starter

PREFERRED QUALIFICATIONS

• Experience with 3D culture models is an asset
• Experience with genomic analysis and database analysis are assets
• Experience in molecular biology is an asset
  TO :
  Please send a cover letter and CV (which includes list of publications) and the contact information for three references attention to Ing Swie Goping, PhD.
  At the University of Alberta, we are committed to creating an inclusive and accessible hiring process for all candidates. If you require accommodations to participate in the interview process, please let us know at the time of booking your interview and we will make every effort to accommodate your needs.
  We thank all applicants for their interest; however, only those individuals selected for an interview will be contacted.
  The University of Alberta is committed to an equitable, diverse, and inclusive workforce. We welcome applications from all qualified persons. We encourage women; First Nations, Métis and Inuit persons; members of visible minority groups; persons with disabilities; persons of any sexual orientation or gender identity and expression; and all those who may contribute to the further diversification of ideas and the University to apply

• Key role in generating PDOs from primary breast cancer patient samples in collaboration with other team members
• Independently responsible for morphological characterization of tissue samples and PDOs by microscopic methods paired to live cell imaging, immunofluorescence, and immunohistochemistry
• Independently responsible for drug-response phenotyping of PDOs and biochemical and cell-based characterization
• Key role in facilitating molecular characterization of PDOs (whole-genome sequencing and RNA-sequencing)
• Independently responsible for data analysis, statistical analysis, data presentation
• Key role in organizing resources and collaborating with team members