Postdoc in molecular microbiology and bacteria-phage interactions

at  KU SCIENCE PLEN

The Environmental Microbial Group (EMG) at the Department of Plant and Environmental Sciences (PLEN), Section for Microbial Ecology and Biotechnology at the University of Copenhagen is offering a 21-month postdoc position within the field of bacteria-phage interactions.
The position will be located at PLEN, but will be in strong collaboration with The Molecular Microbial Ecology Group (MME) at the Department of Biology (BIO), Section for Microbiology at the University of Copenhagen.
Bacteriophages (phages) are viral parasites that infect and kill bacteria, which might cause huge production losses in industrial facilities relying on the use of bacteria in fermentation practices. Bacteria constantly develop diverse anti-phage defense systems, but as a response, phages evolve an arsenal of counter-defense strategies. With this project, funded by the Novo Nordisk Foundation, we aim to investigate the dynamics of phage-bacterial co-evolution and explore the impact of bacterial immune defenses against phages. Our tasks will involve screening and characterizing novel anti-phage defense systems, as well as engineering combinations of defenses in industrially relevant strains to enhance their resilience towards phage infections.
The candidate will be expected to conduct independent research within the area of bacterial genetics, phage biology, and molecular microbiology. The candidate will identify putative bacterial anti-phage defense systems by a combined bioinformatic and experimental approach. Bioinformatic work will be conducted in close collaboration with Assistant Prof. Rafael Pinilla-Redondo at the Section for Microbiology. Experimental work will be conducted at PLEN and includes high-throughput functional validation screening approaches and molecular characterization of anti-phage defense system candidates. Further, the candidate is expected to engage in teaching and supervision.
Candidates must have a PhD or similar qualifications within molecular microbiology, bacterial genetics, phage biology, bacteria-phage interactions, anti-phage defense systems, or other relevant research fields. Laboratory experience with different cloning techniques, functional genomic screenings, molecular work in Escherichia coli , Pseudomonas aeruginosa , Lactococcus lactis and/or Bacillus subtilis, DNA sequencing (Illumina and PacBio), and phage work is strongly desirable. Also, experience or interest in bioinformatics is preferred.
The candidate is expected to be enthusiastic about working in an interdisciplinary academic environment conducting research and teaching at the highest international level. The position, therefore, requires a highly motivated scientist who is comfortable working in teams, has good interpersonal skills, as well as a collaborative and open mindset.
Further information on the Departments is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/ . Inquiries about the position can be made to Associate Prof. Leise Riber, Department of Plant and Environmental Sciences. E-mail: lriber@plen.ku.dk . Phone: +45 40220068, or Assistant Prof. Rafael Pinilla-Redondo, Department of Biology. E-mail: rafael.pinilla@bio.ku.dk . Phone: +4561729969.
The position is open from 1July 2024 or as soon as possible thereafter.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Please refer the Job description for details