Postdoc Positions: Next-generation Single-molecule Imaging

at  Springer Nature

POSTDOC POSITIONS: NEXT-GENERATION SINGLE-MOLECULE IMAGING

Employer
Memorial Sloan Kettering Cancer Center (MSKCC)
Location
New York City, New York (US)
Salary
$61,150-$80,315
Closing date
10 May 2024
Discipline
Biomedicine, Chemistry, Health Science, Life Science, Physics
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Academia
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Pay Range
$61,150-$80,315
Company Overview
The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe. One of the world’s most respected comprehensive centers devoted exclusively to cancer, we have been recognized as one of the top two cancer hospitals in the country by U.S. News & World Report for more than 30 years.
Job Description
We are seeking to recruit outstanding Postdoctoral Fellows/Associates to join us in the Pertsinidis lab in the Structural Biology Program at Sloan Kettering Institute/MSKCC in New York City.
Our lab develops cutting-edge single-molecule detection and super-resolution optical imaging techniques, and applies these tools to visualize and understand some of the most fundamental biological processes that power cellular life. Examples include modulation interferometry, a single-molecule localization-based super-resolution technique with 1-2 nm 3D precision and target-locking 3D nanoscopy, a technique that achieved single-molecule detection in high background, crowded intracellular environments. These tools have enabled some of the highest resolution single-molecule studies to date, providing new biological insights that could not be obtained before (e.g. Wang et al., Cell 2016; Li et al., Cell 2019).
You will have the chance to become an important member of our vibrant, interdisciplinary team, comprising multiple physical and biological scientists. You will have the opportunity to break new grounds in optical imaging, in situ structural biology and biological discovery. Some current interests:
1) building the next-generation single-molecule techniques - to visualize biological processes in live cells with (sub)-millisecond temporal and (sub)-nanometer 3D spatial resolution;
2) pushing the limits of extracting high-resolution information from weak signals in optically inhomogeneous, multi-cellular environments - tissue explants, 3D organoids and developing embryos;
3) constructing novel single-molecule imaging-based discovery platforms, for both basic biology as well as important biomedical applications (drug discovery, cell-based therapeutics);
4) developing new single-molecule imaging and machine learning technologies for in situ structural biology - to enable for the first time high-resolution structural studies inside cells.

Requirements:

• Desire to tackle outstanding challenges in optics, microscopy and/or single-molecule biology
• PhD degree in Physics, Chemistry, Optics, Optical Engineering, Biophysics or a relevant scientific or engineering field.
• Ability to work effectively in a collaborative, multidisciplinary environment.

If you have questions about this opportunity, please reach out to:
Dr. Alexandros Pertsinidis
(PertsinA@mskcc.org)
Please include in this application a CV, names and contact information of three references, and a short description of scientific interests

Salary Range: $61,150-$80,315

• Staff working at a MSK New Jersey location must be up to date with COVID-19 vaccination, which includes having completed the primary COVID-19 vaccination series and booster once eligible as mandated by New Jersey State. All New Jersey staff not yet eligible for a booster must receive a booster within 3 weeks of becoming eligible as a condition of continued employment at MSK.

Note: Individuals are eligible to receive a COVID-19 booster two months after completion of a primary vaccination series for COVID-19. Because vaccine-induced immunity can wane over time, MSK continues to strongly urge all staff to get a COVID-19 booster as soon as they become eligible to maintain their protective immunity for a longer period.
Closing

Please refer the Job description for details