Postdoctoral Fellow - Cell Biology

at  University of Alberta

Department Faculty of Medicine & Dentistry - Cell Biology Dept
Posted date January 9, 2023
Closing date Will remain open until filled.
Position Type Full Time - Trust Funded

POSITION SUMMARY

Redox control of Endoplasmic Reticulum – Mitochondria Contacts and their Relevance for Neurodegeneration
A postdoc position is available immediately to study calcium and redox signaling between the Endoplasmic Reticulum and Mitochondria in the Simmen laboratory (Department of Cell Biology, University of Alberta). The successful applicant will be studying the function of redox-sensitive ER proteins in this mechanism. These proteins localize to ER-mitochondria contact sites dependent on oxidation and reduction of cysteines. A special focus interest will be on the significance of this mechanism for the crosstalk between various CNS cell types, using co-culture approaches. Candidate proteins, novel or identified by the lab previously (e.g., TMX1, PERK, Ero1), will have to be mechanistically characterized using yeast and/or mammalian cell culture; more details are available in our publications and on our websites http://www.ualberta.ca/CELLBIOLOGY/simmen.html
Minimal requirements are previous experience with cell biology, potentially with yeast and two first author publications in an international journal. Applicants need to provide a cover letter that outlines their career objectives and how they would address the questions associated with the project, CV and scanned university grades. Primarily, this position is for Canadian nationals or permanent residents. Outstanding applicants from abroad will be considered but must have excellent English knowledge both spoken and written (high TOEFL/GRE scores or equivalent).
The location of the job is at the University of Alberta, the 5th largest university in Canada with world-class biomedical research labs. Edmonton is a culturally vibrant, young city that lies in close proximity to the Rocky Mountains, offering excellent opportunities for sports enthusiasts.
At the University of Alberta, we are committed to creating an inclusive and accessible hiring process for all candidates. If you require accommodations to participate in the interview process, please let us know at the time of booking your interview and we will make every effort to accommodate your needs.
We thank all applicants for their interest; however, only those individuals selected for an interview will be contacted.
The University of Alberta is committed to an equitable, diverse, and inclusive workforce. We welcome applications from all qualified persons. We encourage women; First Nations, Métis and Inuit persons; members of visible minority groups; persons with disabilities; persons of any sexual orientation or gender identity and expression; and all those who may contribute to the further diversification of ideas and the University to apply

Please refer the Job description for details