Principal Research Scientist

at  Elanco

POSITION DESCRIPTION:

Drive and influence for successful identification and design of novel small molecule drug candidates for clinical development, utilizing a complementary set of in silico, in vitro and in vivo tools and datasets within a matrix environment inclusive of internal and external collaboration partners. Actively support the research portfolio, project strategies, and initiatives that contribute to the success of Elanco R&D.

MINIMUM QUALIFICATION (EDUCATION, EXPERIENCE AND/OR TRAINING, REQUIRED CERTIFICATIONS):

• PhD in Organic /Medicinal Chemistry or equivalent postgraduate education.
• Minimum 8-10 years of demonstrated success in functional area of responsibility in industry (Drug Discovery / Research)
• Excellent knowledge in Medicinal Chemistry related to various therapeutic areas (e.g. dermatology, pain, parasiticides) and supporting functions (e.g. ADME, molecular biology, pharmacology)
• High drive for innovation with growth mindset
• Effective oral and written communication skills
• Good understanding of IP strategy
• Exceptional problem solving and decision making skills

FUNCTIONS, DUTIES, TASKS:

• Generate, support or lead global projects focused on the design and progression of small molecule drug candidates across Elanco research activities (multi parameter optimization)
• Manage allocation and capacity of the external chemistry resources to ensure timelines and key milestones.
• Work with the head of small molecules discovery to ensure resource alignment with project prioritization schemes (scope - SAR plans, timelines, resources & risk/mitigation/contingencies).
• Ensure constant flow of new research projects aligned with R&D strategy, by reviewing literature and external sources of innovation (academia, biotech/phama and agricultural companies) for new chemistry targets or platforms; contribute to Elanco Research strategies and goals.
• Provide scientific input and guidance to external project sources for portfolio entry into the companion and food animal research efforts.
• Identify and implement relevant technologies, methods and strategies in the respective discipline. Continuously improve technical expertise in the function. Proactively initiates value-added work to simplify processes, build capabilities and/or drive the portfolio.
• Maintain and foster sound working relationships within Research and to other functions such as Computational Science / Pharmacokinetics, Pharmacology/ Parasiticides, Safety, and External Innovation.
  Ensure compliance with internal and external guidelines regarding quality and safety (quality manuals, good research principles, health authority guidance and SOPs).