Research Assistant, B-Cell

at  Teva Pharmaceuticals

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Research Assistant, B-Cell
Date: May 21, 2024
Location:Sydney, Australia, 2113
Company: Teva Pharmaceuticals
Job Id: 56069

WHO WE ARE

Together, we’re on a mission to make good health more affordable and accessible, to help millions around the world enjoy healthier lives. It’s a mission that bonds our people across nearly 60 countries and a rich, diverse variety of nationalities and backgrounds. Working here means working with the world’s leading manufacturer of generic medicines, and the proud producer of many of the products on the World Health Organization’s Essential Medicines List. Today, at least 200 million people around the world take one of our medicines every single day. An amazing number, but we’re always looking for new ways to continue making a difference, and new people to make a difference with.

THE OPPORTUNITY

We are seeking a research assistant to join TEVA’s growing speciality R&D, antibody discovery program in Sydney, Australia.
You will conduct R&D on therapeutic antibody discovery projects with a focus on single B cell screening workflows by employing antibody expression, characterisation, and purification techniques

YOUR EXPERIENCE AND QUALIFICATIONS

• A Bachelor in life sciences with a relevant Honours or Master’s degree
• In depth knowledge of recombinant protein expression, purification and performing quality assessments required.
• High level of proficiency and experience in Flow Cytometry
• Strong experience in mammalian cell culture techniques
• Previous experience with SPR techniques and/or ELISA will be highly regarded.
• Additional knowledge of molecular biology techniques will be advantageous.
• Excellent attention to detail, good communication, documentation skills and ability to multi-task
• Keen interest in learning new technology and an imagination for practical application will be highly valued.
• Excellent ability to organize and prioritize tasks across multiple projects and deliver according to timelines.
• Team player with flexible approach to work in a dynamic work environment

• Expression and screening of antibodies
• Mammalian cell expression and purification of recombinant antibodies
• Antibody screening using Flow Cytometry, Surface Plasmon Resonance and ELISA
• Antibody characterisation by chromatographic methods
• Development of assays for single cell screening platforms
• Generation of reagents for immunisation and screening
• Preparation and purification of DNA
• General tissue culture and maintenance of mammalian cell lines
• Isolate mouse B cells using cell sorting, including B cell staining and data analysis.
• Conduct single B cell screens, export, and transfer hits for sequencing.
• Work hand in hand with other teams including cell-based assays, protein science to ensure project goals and timelines are met.
• Provide regular updates in the form of presentations.
• Compliance with all employee health and safety, PC2 and gene technology guidelines including adherence to TEVA policies and procedures.
• Corporate citizenship, including serving on in-house committees.
• Continuous development learning new skills and support R&D organization with other tasks when needed