Research Assistant in Molecular Neurodevelopmental Research

at  Institut fr Molekulare Biologie gGmbH

THE POSITION

Deciphering the role of BAF complexes in human brain development and neurodevelopmental disorders.
As part of the chromatin regulation group, you will be working on a project addressing the role of BAF chromatin remodelling complexes in human brain development and related diseases. As a model system, you will use the differentiation of human induced pluripotent stem cell (hiPSC) into brain organoids in combination with genetic and pharmacological perturbations. Advanced cell and molecular biology techniques, including bulk and single cell genomics, proteomics and microscopy, will be used to unravel the cellular and molecular mechanisms driven by BAF chromatin remodelers.
We are looking for a researcher to work with us for at least 6 months, with the possibility of continuing as a PhD student or postdoctoral researcher.

REQUIREMENTS

• Highly motivated and creative researcher who enjoys bench-work
• Basic experience in cell culture techniques is highly beneficial
• Enthusiasm about science especially with regard to neurodevelopmental processes, gene regulation and epigenetics
• Ability to work precisely and good attention to detail
• Ability to work independently after an initial training period
• Very good oral and written communication skills in English
• Computational skills are an asset but not compulsory

WHAT ELSE YOU NEED TO KNOW

• Starting Date: May 2024 or later
• Duration: at least 6 months
• Deadline: 15th April 2024

• hiPSC culture and organoid differentiation
• Planning, optimization and execution of various state-of-the-art molecular and cellular biology methods
• Data analysis, documentation and presentation
• Regularly participate and present at (internal) meetings
• Study of relevant scientific literature