Research Associate

at  McGill University

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Position Summary:

The Reinhardt laboratory is interested in components and mechanisms involved in the biogenesis, function and pathological aspects of the extracellular matrix and its interactions with cells. The research themes rank around molecular mechanisms matrix proteins and fibers exert in disorders affecting blood vessels, bone, skin and adipose tissue. We are interested how extracellular matrix proteins instruct cells to differentiate, migrate, and proliferate, and how cells sense normal and pathologically altered extracellular matrix. We are interested in recruiting for a Research Associate who will be responsible for the following tasks:

• Analysis of mouse models with respect to bone and adipose tissue biology
• Bone fracture healing studies on genetically modified mouse models
• High-fat diet studies on genetically modified mouse models
• Generation of new genetically modified mouse models
• Preparation and extraction of mouse tissues for RNA, protein, and immunohistological analyses
• Preparation and analyses of stem cells from mouse bone marrow and adipose tissues
• Analyses of induced pluripotent stem cells as disease models
• Generation of new plasmids for the recombinant expression of extracellular matrix proteins (e.g., deletion mutants of fibulin-5, LTBP4, and fibrillin-1)
• Generation of stable recombinant cell clones in 293 and CHO cells
• Purification and characterization of the recombinant proteins
• Generation of ideas for new projects
• Writing grant applications and manuscripts
• Teaching undergraduate and graduate students various laboratory techniques
• Contributing to general lab organization

Qualifications:

• PhD relevant in extracellular matrix biology
• 5 years of relevant research experience in bone and adipose tissue biology

Knowledge of French and English: McGill University is an English-language university where day to day duties may require English communication both verbally and in writing. The level of English required for this position has been assessed at a level 4 on a scale of 0-4.
Hourly Salary:
$44.11
Hours per Week:
26.25 (Part time)
Location:
Strathcona Anat&Dent
Supervisor:
Professor
Position Start Date:
2024-05-27
Position End Date:
2025-05-26
Deadline to Apply:
2024-05-10
This position is covered by the Association of McGill University Research Employees (AMURE) collective agreement.
McGill University hires on the basis of merit and is strongly committed to equity and diversity within its community. We welcome applications from racialized persons/visible minorities, women, Indigenous persons, persons with disabilities, ethnic minorities, and persons of minority sexual orientations and gender identities, as well as from all qualified candidates with the skills and knowledge to productively engage with diverse communities. McGill implements an employment equity program and encourages members of designated groups to self-identify. Persons with disabilities who anticipate needing accommodations for any part of the application process may contact, in confidence,
accessibilityrequest.hr@mcgill.ca

• Analysis of mouse models with respect to bone and adipose tissue biology
• Bone fracture healing studies on genetically modified mouse models
• High-fat diet studies on genetically modified mouse models
• Generation of new genetically modified mouse models
• Preparation and extraction of mouse tissues for RNA, protein, and immunohistological analyses
• Preparation and analyses of stem cells from mouse bone marrow and adipose tissues
• Analyses of induced pluripotent stem cells as disease models
• Generation of new plasmids for the recombinant expression of extracellular matrix proteins (e.g., deletion mutants of fibulin-5, LTBP4, and fibrillin-1)
• Generation of stable recombinant cell clones in 293 and CHO cells
• Purification and characterization of the recombinant proteins
• Generation of ideas for new projects
• Writing grant applications and manuscripts
• Teaching undergraduate and graduate students various laboratory techniques
• Contributing to general lab organizatio