Research Investigator (In-Vitro Pharmacology), London

at  Isomorphic Labs

YOUR IMPACT

Isomorphic labs are seeking exceptional individuals to join an impactful in-vitro pharmacology sub team within our translational science team working in multidisciplinary ML based drug discovery medical research.
These roles would be ideal for experienced in-vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell based functional assays who have extensive experience of providing quantitative in-vitro pharmacology expertise within drug discovery projects.
This is an exciting opportunity to work closely with world leading AI, ML and drug discovery experts to develop imaginative new ways to test biological hypotheses building a deep mechanistic understanding of drug target interactions to drive our projects forward. You will play a key pivotal role in defining the screening cascades for our drug design projects, advancing our oncology, immunology and partnership portfolios from early Drug Discovery through to Candidate Selection and ultimately to Clinical Phase work.
You will have experience of working broadly across drug discovery projects and have the ability to think originally and critically, knowing when to apply innovative ideas, and think with a beginners’ approach.

• Design efficient and comprehensive biological screening cascades for a variety of internal and partnered drug design programs
• Work with CROs to design decision-making experiments, and deliver the highest quality biological data to inform the path to the clinic
• Provide expertise to the AI/ML teams in developing world leading models of biological systems
• Distil biological data into useful insights for project teams and ML research
• Be closely integrated within or be leading projects to provide strategic input to deliver project success
• Contribute relevant internal and supporting regulatory documentation for preclinical and clinical work
• Work cross-functionally with our Drug Design and Technology teams