Research Scientist – Protein Engineering and Novel Modalities

at  AstraZeneca

ACCOUNTABILITIES:

As a Research Scientist, your experience in the application of protein, molecular biology and/or biophysical skill sets will be crucial in designing and characterising the next generation of biologics, with a focus on multi-specific molecules and cellular engagers. You will execute experiments efficiently, analyse, interpret, and present data and ideas to a wider audience.

ESSENTIAL SKILLS/EXPERIENCE:

• Graduate level scientist with hands-on laboratory-based experience
• Awareness of antibody structure-function relationships
• Hands-on experience in molecular biology methods and technologies e.g., PCR, RT-PCR, cloning (ligation-dependent and independent methods), site-directed mutagenesis, Sanger sequencing/analysis, and/or, experience in common expression systems (e.g. mammalian), purification methods (e.g. Akta systems), and/or the ability to profile constructs (e.g. SPR; biochemical assays)
• Ability to apply protocols, troubleshoot, interpret experimental results/data and maintain accurate, high quality and up-to-date experimental records
• Strong communication skills in a team environment and an ability to quickly learn and adopt new technologies

DESIRABLE SKILLS/EXPERIENCE:

• Experience of laboratory-based research in the pharmaceutical industry
  When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. The role is lab-based and requires you to be present on-site.

Are you ready to take a crucial inter-disciplinary approach to deliver life-changing medicines? We are seeking a highly motivated Research Scientist to help support our Respiratory and Immunology discovery pipeline. The role will involve developing and implementing our next-generation modalities in their application to pre-clinical programs.