Research Technician - Wilson Lab

at  Springer Nature

RESEARCH TECHNICIAN - WILSON LAB

Employer
Howard Hughes Medical Institute (HHMI)
Location
Boston, Massachusetts
Salary
$17.72 - $28.77 per hour
Closing date
10 Jun 2024
Discipline
Life Science
Job Type
Research Assistant
Employment - Hours
Full time
Duration
Permanent
Qualification
Undergraduate
Sector
Academia
You need to sign in or create an account to a job.
The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all. As a biomedical research organization and philanthropy, HHMI supports a vibrant community of academic researchers, educators, students, and professionals. Together, we’re unlocking the fundamentals of biology and building an open, inclusive future for science.
We are currently looking for a Research Technician to join the lab of Dr. Rachel Wilson at Harvard Medical School. Dr. Wilson and her team of scientists are working to understand how the brain performs fundamental computations related to navigation, spatial memory, and visuo-motor control. They use the fruit fly Drosophila melanogaster to investigate these questions using genetic tools and analyses of large-scale connectome data to target specific cells for investigation. Neural activity is monitored using in vivo intracellular electrophysiological recordings and calcium imaging while flies navigate in virtual reality environments. Because many neural systems in various species face the same constraints, it is likely that the lessons we learn from this simple brain will provide clues to understanding similar problems in more complex brains, including the human brain. More information about the lab and their work can be found by visiting https://wilson.hms.harvard.edu/

PHYSICAL REQUIREMENTS

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.
Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

PLEASE NOTE:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.

ABOUT THE RESEARCH TECHNICIAN ROLE:

Recently, new genetic tools have emerged which open the door to new experiments that were never before possible. To use these tools, we need a team member to assist us in screening genetically modified flies and generating novel genetic combinations. This position offers the opportunity to learn cutting-edge neuroscience techniques, to become broadly knowledgeable about neuroscience, and to work as part of a tight-knit team of energetic, experienced research scientists – an ideal fit for a hardworking, passionate individual who is looking for a robust 2+ year career experience with the lab before beginning graduate school, medical school, or the next step of their professional journey.

WHAT YOU’LL DO:

• Visually screening databases of anatomical images of Drosophila brain cell types
• Genetic engineering to combine transgenes from different genetically-modified Drosophila to create novel brain labeling patterns
• Dissecting brains and performing immunostaining protocols to label genetically-tagged brain cells
• Optimizing immunostaining protocols for new cell types and new genetic markers Imaging labeled brains using laser-scanning multicolor confocal microscopy.
• Analyzing confocal images by comparing them with large-scale electron microscopy data
• Logging data into a shared information-storage system for other team members to view
• Contributing ideas to group discussions about research strategy
• Contributing feedback to manuscripts
• Training other team members in these job tasks