Scientist II

at  Wapt

Overview:
HD Biosciences Inc. a WuXi AppTec company, is a fast growth, fast paced biology-focused preclinical drug discovery contract research organization (CRO). We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services. We are seeking a highly motivated and skilled Scientist I or Scientist II to perform Liquid Chromatography Mass Spectrometry (LCMS) bioanalysis studies.

Responsibilities:

• Works on assignments with a diverse team of scientists to facilitate all aspects of performing LCMS bioanalysis studies
• Ability to run assays based on established protocols
• Performs preliminary lab work independently
• Performs routine calculations, tabulates, and records results.
• Assumes responsibility for technical accuracy of work.
• Maintains, calibrates laboratory equipment and coordinates maintenance with vendors
• Develops new methods or assays based on minimal information or protocols.
• Maintains research notebooks in a well-organized manner, ensures all necessary documentation is recorded.
• Makes decisions based on an understanding of client program goals.
• Communicates frequently with client and provide frequent update reports.
• Makes logical suggestions of likely causes of problems and independently suggests solutions.
• Ability to learn and instruct Associate Scientists in the use of semi-automated liquid dispensers, plate readers, and other lab instruments
• Complies with all safety rules, practices good housekeeping, and maintains safe workplace without supervision.
• Self-Motivated, requires minimal supervision and determines next steps with minimal guidance

Qualifications:

• PhD 1 with 3+ or MS degree 6+ or BS degree 8+ years of experience in LCMS based assay development and biological sciences

KNOWLEDGE / SKILLS / ABILITIES:

• Must possess skills in the following areas:
  o Solid understanding of qualitative and quantitative LCMS workflows in small molecule, lipidomics, glycomics and proteomics with associated sample preparation techniques
  o Solid competency in a broad range of LCMS instrumentation such as QQQ, QTOF and orbitrap and application solutions
  o Biophysical techniques such as SPR a plus

o Biochemical and cell-based assay in high density plates a plus

• Demonstrates competence in relevant technical aspects of scientific discipline which allows for increasing level of independence
• Records experimental procedures and results in notebook
• Demonstrates attention to details and concern for impact
• Knowledge of commonly used concepts, practices, and procedures within biological R&D laboratory setting
• Presents data clearly and concisely
• Effectively communicates with others by giving and receiving feedback
• Must work well with others in a team environment
• Participates actively in meetings
• Able to work in a fast paced environment
• Well organized, detail oriented, and adaptable to changes
• Excellent oral and written communication skills
• Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint. Ability to learn instrument and data analysis software
• Good time management and multi-tasking skills in order to complete multiple projects within timelines.
• Ability to effectively prioritize workload and manage changes in direction
• Ability to think critically and scientifically
• Ability to search scientific literature and suggest protocols and methods
• Regularly reviews goals and objectives with supervisor

Anticipated base pay range: $80,322 to $104,011

• Works on assignments with a diverse team of scientists to facilitate all aspects of performing LCMS bioanalysis studies
• Ability to run assays based on established protocols
• Performs preliminary lab work independently
• Performs routine calculations, tabulates, and records results.
• Assumes responsibility for technical accuracy of work.
• Maintains, calibrates laboratory equipment and coordinates maintenance with vendors
• Develops new methods or assays based on minimal information or protocols.
• Maintains research notebooks in a well-organized manner, ensures all necessary documentation is recorded.
• Makes decisions based on an understanding of client program goals.
• Communicates frequently with client and provide frequent update reports.
• Makes logical suggestions of likely causes of problems and independently suggests solutions.
• Ability to learn and instruct Associate Scientists in the use of semi-automated liquid dispensers, plate readers, and other lab instruments
• Complies with all safety rules, practices good housekeeping, and maintains safe workplace without supervision.
• Self-Motivated, requires minimal supervision and determines next steps with minimal guidanc